FAQ

GPC2 gene

Known as: glypican 2, glypican proteoglycan 2, cerebroglycan proteoglycan, DKFZp547M109 
This gene is involved in heparin sulfate binding to cell surfaces.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2016
01219942016

Related topics

Related topics

3 relations
GlypicanGlypican-2, humanLigand Binding

Related mentions per year

Related mentions per year

1977-2018
197019801990200020102020
GPC2 gene
Ligand Binding
Glypican
Glypican-2, human

Papers overview

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2017
2017
Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.
We developed an RNA-sequencing-based pipeline to discover differentially expressed cell-surface molecules in neuroblastoma that… (More)
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2012
2012
Identification of Cell Surface Proteins as Potential Immunotherapy Targets in 12 Pediatric Cancers
Technological advances now allow us to rapidly produce CARs and other antibody-derived therapeutics targeting cell surface… (More)
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2001
2001
Thyroid hormone deficiency alters extracellular matrix protein expression in rat brain.
The effects of thyroid hormone (T3) deficiency on extracellular matrix protein expression were analyzed in newborn rat brain. In… (More)
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1999
1999
Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: assessment of selectivity, heterogeneity and the participation of core proteins in binding.
The method of affinity coelectrophoresis was used to study the binding of nine representative glycosaminoglycan (GAG)-binding… (More)
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1997
1997
Cerebroglycan, a developmentally regulated cell-surface heparan sulfate proteoglycan, is expressed on developing axons and growth cones.
Cerebroglycan is a glycosylphosphatidylinositol-linked integral membrane heparan sulfate proteoglycan found exclusively in the… (More)
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1997
1997
Differential regulation of neuronal proteoglycans by activation of excitatory amino acid receptors.
Cell surface proteoglycans (PGs) have been implicated in neuronal growth, migration and differentiation and can play pivotal… (More)
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1996
1996
Developmental and FGF-2-mediated regulation of syndecans (1-4) and glypican in oligodendrocytes.
Differentiating cells undergo developmentally regulated changes in cell-cell and cell-matrix adhesion that control migration… (More)
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1995
1995
K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney
Glypicans are a family of glycosylphosphatidylinositol (GPI)-anchored cell surface heparan sulfate proteoglycans (HSPGs). The… (More)
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1995
1995
Identification of a new membrane-bound heparan sulphate proteoglycan.
The morphological changes that occur during intestinal development have been extensively described, but the molecular basis of… (More)
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1994
1994
Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation
Heparan sulfate proteoglycans (HSPGs) are found on the surface of all adherent cells and participate in the binding of growth… (More)
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