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GPC3 protein, human

Known as: glypican 3 protein, human, MXR7 protein, human, Intestinal Protein OCI-5 
Glypican-3 (580 aa, ~66 kDa) is encoded by the human GPC3 gene. This protein is involved in the mediation of proteoglycan binding to the cell surface… Expand
National Institutes of Health

Papers overview

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2015
2015
Glypican-3 (GPC3) represents an attractive target for hepatocellular carcinoma (HCC) therapy because it is highly expressed in… Expand
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Highly Cited
2014
Highly Cited
2014
ABSTRACT Glypican-3 (GPC3) is a proteoglycan that is bound to the cell surface. It is expressed by most hepatocellular carcinomas… Expand
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2012
2012
BACKGROUND Distinguishing hepatocellular carcinoma (HCC) from adenocarcinoma in fine-needle aspiration biopsies (FNAB) is often… Expand
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2012
2012
Summary Glypican-3 (GPC3) is a heparan sulfate (HS) proteoglycan that is bound to the cell membrane through a… Expand
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Highly Cited
2008
Highly Cited
2008
Loss-of-function mutations in glypican-3 (GPC3), one of the six mammalian glypicans, causes the Simpson-Golabi-Behmel overgrowth… Expand
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Highly Cited
2005
Highly Cited
2005
Loss-of-function mutations of the GPC3 gene are the cause of the human Simpson-Golabi-Behmel syndrome. Based on the overgrowth… Expand
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2003
2003
Glypican-3 (GPC3) encodes a cell-surface heparan-sulfate proteoglycan mutated in type 1 Simpson-Golabi-Behmel syndrome (SGBS1… Expand
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Highly Cited
2000
Highly Cited
2000
Gene expression changes in rat asbestos-induced malignant mesothelioma (MM) cells were investigated by differential mRNA display… Expand
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Highly Cited
2000
Highly Cited
2000
Glypicans represent a family of six cell surface heparan sulfate proteoglycans in vertebrates. Although no specific in vivo… Expand
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Highly Cited
1997
Highly Cited
1997
Using the differential display method to analyze mRNA expression in hepatocellular carcinoma (HCC) and nontumor livers, we cloned… Expand
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