Glycochenodeoxycholic Acid

Known as: Acid, Glycochenodeoxycholic, Glycochenodeoxycholic Acid [Chemical/Ingredient], Chenodeoxycholylglycine 
A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for… (More)
National Institutes of Health

Papers overview

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2015
2015
Accumulation of bile acids is a major mediator of cholestatic liver injury. Recent studies indicate bile acid composition between… (More)
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2009
2009
Apoptosis induced by hydrophobic bile acids is thought to contribute to liver injury during cholestasis. Caspase-6 is an… (More)
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2006
2006
In chronic cholestatic liver diseases, accumulation of hydrophobic bile acids is thought to damage hepatocytes. The mechanism of… (More)
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Highly Cited
2006
Highly Cited
2006
The multidrug resistance protein ABCC4 (MRP4), a member of the ATP-binding cassette superfamily, mediates ATP-dependent… (More)
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Highly Cited
2005
Highly Cited
2005
The accumulation of hydrophobic bile acids results in cholestatic liver injury by increasing oxidative stress, mitochondrial… (More)
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Highly Cited
2004
Highly Cited
2004
Ursodeoxycholic acid (UDCA) is used in the treatment of cholestatic liver diseases, but its mechanism of action is not yet well… (More)
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Highly Cited
2001
Highly Cited
2001
The accumulation of hydrophobic bile acids plays a role in the induction of apoptosis and necrosis of hepatocytes during… (More)
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2001
2001
Hydrophobic bile acids may cause hepatocellular necrosis and apoptosis during cholestatic liver diseases. The mechanism for this… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Reflux of duodenal contents into the esophagus of patients with gastroesophageal reflux disease has been suggested by… (More)
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Highly Cited
1987
Highly Cited
1987
A reversed phase high pressure liquid chromatography (HPLC) system capable of simultaneously separating four lithocholyl species… (More)
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