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Glycine Chenodeoxycholate

Known as: Chenodeoxycholate, Glycine, Glycochenodeoxycholate 
 
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
The plasma profile of subjects with nonalcoholic fatty liver disease (NAFLD), steatosis, and steatohepatitis (NASH) was examined… Expand
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Highly Cited
2007
Highly Cited
2007
Nuclear factor kappa B (NF-kappaB) is a redox-associated transcription factor that is involved in the activation of survival… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND & AIMS The bile salt export pump (BSEP) is the major bile salt transporter in the liver canalicular membrane. Our aim… Expand
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Highly Cited
2000
Highly Cited
2000
Toxic bile salts induce hepatocyte apoptosis by a Fas-dependent, Fas ligand-independent mechanism. To account for this… Expand
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Highly Cited
1999
Highly Cited
1999
Cholestatic liver injury appears to result from the induction of hepatocyte apoptosis by toxic bile salts such as… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS Bile salt-induced apoptosis is mediated by a trypsin-like nuclear protease. The aims of this study were to… Expand
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Highly Cited
1995
Highly Cited
1995
Ursodeoxycholate (UDCA), a hydrophilic bile salt, ameliorates hepatocellular injury by toxic bile salts and is used to treat… Expand
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Highly Cited
1993
Highly Cited
1993
Chenodeoxycholate is toxic to hepatocytes, and accumulation of chenodeoxycholate in the liver during cholestasis may potentiate… Expand
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Highly Cited
1990
Highly Cited
1990
Primary human hepatocytes were used to study bile salt hepatotoxicity and the hepatoprotective potential of ursodeoxycholate in… Expand
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Highly Cited
1971
Highly Cited
1971
SummaryThe solubility of cholesterol in aqueous solutions of bile salts and lecithin with N/10 phosphate buffer, pH 7.3 has been… Expand
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