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- Publications
- Influence
Host-Gut Microbiota Metabolic Interactions
- J. Nicholson, E. Holmes, +4 authors S. Pettersson
- Biology, Medicine
- Science
- 8 June 2012
The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut… Expand
Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
- T. Wang, G. Cai, +6 authors Liping Zhao
- Biology, Medicine
- The ISME Journal
- 1 February 2012
Despite a long-suspected role in the development of human colorectal cancer (CRC), the composition of gut microbiota in CRC patients has not been adequately described. In this study, fecal bacterial… Expand
Symbiotic gut microbes modulate human metabolic phenotypes
- M. Li, B. Wang, +23 authors Liping Zhao
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 12 February 2008
Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated in disease… Expand
Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS.
Colorectal carcinogenesis involves the overexpression of many immediate-early response genes associated with growth and inflammation, which significantly alters downstream protein synthesis and… Expand
Temporal Regulation of Intracellular Organelle Homeostasis in T Lymphocytes by Autophagy
- W. Jia, You-Wen He
- Biology, Medicine
- The Journal of Immunology
- 1 May 2011
The highly conserved self-degradation pathway known as autophagy plays important roles in regulating T lymphocyte homeostasis. Recently, we found that T lymphocytes lacking the autophagy-related gene… Expand
Antidiabetic herbal drugs officially approved in China
- W. Jia, Wenyuan Gao, L. Tang
- Medicine
- Phytotherapy research : PTR
- 1 December 2003
Over the centuries, Chinese herbal drugs have served as a major source of medicines for the prevention and treatment of diseases including diabetes mellitus (known as ‘Xiao‐ke’). It is estimated that… Expand
Completed robust local binary pattern for texture classification
- Y. Zhao, W. Jia, Rong-Xiang Hu, Hai Min
- Computer Science
- Neurocomputing
- 1 April 2013
TLDR
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
Emerging evidence points to a strong association between the gut microbiota and the risk, development and progression of gastrointestinal cancers such as colorectal cancer (CRC) and hepatocellular… Expand
Serum and Urine Metabolite Profiling Reveals Potential Biomarkers of Human Hepatocellular Carcinoma*
Hepatocellular carcinoma (HCC) is a common malignancy in the world with high morbidity and mortality rate. Identification of novel biomarkers in HCC remains impeded primarily because of the… Expand
Distinct urinary metabolic profile of human colorectal cancer.
A full spectrum of metabolic aberrations that are directly linked to colorectal cancer (CRC) at early curable stages is critical for developing and deploying molecular diagnostic and therapeutic… Expand