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Host-Gut Microbiota Metabolic Interactions
The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gutExpand
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Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
Despite a long-suspected role in the development of human colorectal cancer (CRC), the composition of gut microbiota in CRC patients has not been adequately described. In this study, fecal bacterialExpand
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Symbiotic gut microbes modulate human metabolic phenotypes
  • M. Li, B. Wang, +23 authors Liping Zhao
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 12 February 2008
Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated in diseaseExpand
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Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS.
  • Y. Qiu, G. Cai, +8 authors W. Jia
  • Chemistry, Medicine
  • Journal of proteome research
  • 4 September 2009
Colorectal carcinogenesis involves the overexpression of many immediate-early response genes associated with growth and inflammation, which significantly alters downstream protein synthesis andExpand
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Temporal Regulation of Intracellular Organelle Homeostasis in T Lymphocytes by Autophagy
The highly conserved self-degradation pathway known as autophagy plays important roles in regulating T lymphocyte homeostasis. Recently, we found that T lymphocytes lacking the autophagy-related geneExpand
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Antidiabetic herbal drugs officially approved in China
Over the centuries, Chinese herbal drugs have served as a major source of medicines for the prevention and treatment of diseases including diabetes mellitus (known as ‘Xiao‐ke’). It is estimated thatExpand
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Completed robust local binary pattern for texture classification
This paper proposes a robust framework of LBP, named Completed Robust Local Binary Pattern (CRLBP), in which the value of each center pixel in a 3x3 local area is replaced by its average local gray level. Expand
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Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
  • W. Jia, G. Xie, W. Jia
  • Biology, Medicine
  • Nature Reviews Gastroenterology & Hepatology
  • 1 February 2018
Emerging evidence points to a strong association between the gut microbiota and the risk, development and progression of gastrointestinal cancers such as colorectal cancer (CRC) and hepatocellularExpand
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Serum and Urine Metabolite Profiling Reveals Potential Biomarkers of Human Hepatocellular Carcinoma*
  • T. Chen, G. Xie, +11 authors W. Jia
  • Biology, Medicine
  • Molecular & Cellular Proteomics
  • 25 April 2011
Hepatocellular carcinoma (HCC) is a common malignancy in the world with high morbidity and mortality rate. Identification of novel biomarkers in HCC remains impeded primarily because of theExpand
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Distinct urinary metabolic profile of human colorectal cancer.
A full spectrum of metabolic aberrations that are directly linked to colorectal cancer (CRC) at early curable stages is critical for developing and deploying molecular diagnostic and therapeuticExpand
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