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Glucosephosphate Dehydrogenase

Known as: Dehydrogenase, Glucose-6-Phosphate, G6PD, glucose-6-phosphate dehydrogenase (G6PD) 
Glucose-6-phosphate 1-dehydrogenase (515 aa, ~59 kDa) is encoded by the human G6PD gene. This protein plays a role in pentose metabolism to produce… 
National Institutes of Health

Related topics

Related topics

31 relations

Broader (1)

Alcohol Oxidoreductases
AnabolismAnemiaDeficiency of glucose-6-phosphate dehydrogenaseEnzyme Gene

Narrower (12)

glucose 6-phosphate dehydrogenase Palermo, humanglucose-6-phosphate dehydrogenase A-glucose-6-phosphate dehydrogenase Aveiroglucose-6-phosphate dehydrogenase Calvo Mackenna

Papers overview

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Review
2008
Review
2008
Erythrocyte programmed cell death
Eryptosis, the suicidal death of erythrocytes, is characterised by cell shrinkage, membrane blebbing and cell membrane… 
Highly Cited
2004
Highly Cited
2004
Enhanced phagocytosis of ring-parasitized mutant erythrocytes: a common mechanism that may explain protection against falciparum malaria in sickle trait and beta-thalassemia trait.
High frequency of erythrocyte (red blood cell [RBC]) genetic disorders such as sickle cell trait, thalassemia trait, homozygous… 
Highly Cited
2002
Highly Cited
2002
Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies.
Control genes, commonly defined as genes that are ubiquitously expressed at stable levels in different biological contexts, have… 
Highly Cited
2001
Highly Cited
2001
Haplotype Diversity and Linkage Disequilibrium at Human G6PD: Recent Origin of Alleles That Confer Malarial Resistance
The frequencies of low-activity alleles of glucose-6-phosphate dehydrogenase in humans are highly correlated with the prevalence… 
Highly Cited
1999
Highly Cited
1999
Importance of glucose-6-phosphate dehydrogenase activity in cell death.
The intracellular redox potential plays an important role in cell survival. The principal intracellular reductant NADPH is mainly… 
Highly Cited
1998
Highly Cited
1998
Early phagocytosis of glucose-6-phosphate dehydrogenase (G6PD)-deficient erythrocytes parasitized by Plasmodium falciparum may explain malaria protection in G6PD deficiency.
In population-based studies it has been established that inherited deficiency of erythrocyte (E) glucose-6-phosphate… 
Review
1997
Review
1997
Oxidative damage in chemical teratogenesis.
Highly Cited
1994
Highly Cited
1994
Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Formation of cross-linked protein that inhibits the multicatalytic protease.
Incubation of glucose-6-phosphate dehydrogenase (Glu-6-PDH) from Leuconostoc mesenteroides with the lipid peroxidation product 4… 
Highly Cited
1989
Highly Cited
1989
Protein oxidation and proteolysis during aging and oxidative stress.
Review
1985
Review
1985
Chronic myelogenous leukemia: recent advances.
By R.E. Champlin and OW. Golde C HRONIC myelogenous leukemia (CML) is a hematologic malignancy characterized by excessive growth… 
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