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Glucagon Receptor

Known as: Receptors, Glucagon, Receptor, Glucagon, Glucagon Receptors 
Cell surface receptors that bind glucagon with high affinity and trigger intracellular changes which influence the behavior of cells. Activation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To determine the role of glucagon action in the metabolic phenotype of untreated insulin deficiency. RESEARCH DESIGN… Expand
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE Oxyntomodulin (OXM) is a glucagon-like peptide 1 (GLP-1) receptor (GLP1R)/glucagon receptor (GCGR) dual agonist peptide… Expand
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Highly Cited
2008
Highly Cited
2008
Glucagon receptor (Gcgr) signaling maintains hepatic glucose production during the fasting state; however, the importance of the… Expand
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Highly Cited
2006
Highly Cited
2006
Aims/hypothesisUnder normal physiological conditions, glucagon signalling is important in glucose homeostasis. Hyperglucagonaemia… Expand
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Highly Cited
2004
Highly Cited
2004
Uncontrolled hepatic glucose production contributes significantly to hyperglycemia in patients with type 2 diabetes… Expand
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Highly Cited
2004
Highly Cited
2004
Excess glucagon levels contribute to the hyperglycemia associated with type 2 diabetes. Reducing glucagon receptor expression may… Expand
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Highly Cited
2003
Highly Cited
2003
Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic α cells in response to low blood glucose. To… Expand
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Highly Cited
1999
Highly Cited
1999
Glucagon-like peptide-1 (GLP-1) is derived from the peptide precursor pre-pro-glucagon (PPG) by enzymatic cleavage and acts via… Expand
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Highly Cited
1998
Highly Cited
1998
The regulation of glucose metabolism by glucagon and GLP-1 is well established, but novel functions for these and other… Expand
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Highly Cited
1993
Highly Cited
1993
Glucagon and the glucagon receptor are a primary source of control over blood glucose concentrations and are especially important… Expand
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