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Glucagon Receptor

Known as: Receptors, Glucagon, Receptor, Glucagon, Glucagon Receptors 
Cell surface receptors that bind glucagon with high affinity and trigger intracellular changes which influence the behavior of cells. Activation of… 
National Institutes of Health

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AKHR protein, Drosophila
GCGR geneGlucagonIn Bloodagonists

Papers overview

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Highly Cited
2003
Highly Cited
2003
Three Distinct Epitopes on the Extracellular Face of the Glucagon Receptor Determine Specificity for the Glucagon Amino Terminus*
The glucagon and glucagon-like peptide-1 (GLP-1) receptors are homologous family B seven-transmembrane (7TM) G protein-coupled… 
Highly Cited
2001
Highly Cited
2001
Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase
We prepared a stable cell line expressing the glucagon receptor to characterize the effect of Gs-coupled receptor stimulation on… 
Highly Cited
1999
Highly Cited
1999
Two Cytoplasmic Loops of the Glucagon Receptor Are Required to Elevate cAMP or Intracellular Calcium*
The glucagon receptor is a member of a distinct class of G protein-coupled receptors (GPCRs) sharing little amino acid sequence… 
Review
1998
Review
1998
Histologic distribution of insulin and glucagon receptors.
Insulin and glucagon are the hormonal polypeptides secreted by the B and A cells of the endocrine pancreas, respectively. Their… 
Highly Cited
1992
Highly Cited
1992
Connexins and glucagon receptors during development of rat hepatic acinus.
Levels (by immunoblotting) and cell distribution (by immunofluorescence) of connexins (Cxs) and glucagon receptors (GRs) were… 
1990
1990
Glucagon-(19-29), a Ca2+ pump inhibitory peptide, is processed from glucagon in the rat liver plasma membrane by a thiol endopeptidase.
Highly Cited
1981
Highly Cited
1981
Identification of the glucagon receptor in rat liver membranes by photoaffinity crosslinking.
The photoaffinity crosslinker hydroxysuccinimidyl-p-azidobenzoate was used to attach (125)I-labeled glucagon covalently to a rat… 
Highly Cited
1979
Highly Cited
1979
Effects of phospholipase A2 and filipin on the activation of adenylate cyclase.
Highly Cited
1975
Highly Cited
1975
Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.
Rat liver membrane adenylate cyclase (EC 4.6.1.1) that has been stimulated more than 10-fold by cholera toxin (choleragen) has a… 
1972
1972
Independence of glucagon receptors and glucagon inactivation in liver cell membranes.
THERE is increasing evidence that receptors for polypeptide hormones are localized on the cell membrane. Hormone-receptor… 
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