Glucagon Receptor

Known as: Receptors, Glucagon, Receptor, Glucagon, Glucagon Receptors 
Cell surface receptors that bind glucagon with high affinity and trigger intracellular changes which influence the behavior of cells. Activation of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2017
024619832017

Papers overview

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2016
2016
OBJECTIVE Type 2 diabetes pathophysiology is characterized by dysregulated glucagon secretion. LY2409021, a potent, selective… (More)
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2015
2015
Antagonizing glucagon action represents an attractive therapeutic option for reducing hepatic glucose production in settings of… (More)
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2015
2015
The glucagon and glucagon-like peptide-1 (GLP-1) receptors play important, opposing roles in regulating blood glucose levels… (More)
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2013
2013
Glucagon is a critical regulator of glucose homeostasis; however, mechanisms regulating glucagon action and α-cell function and… (More)
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2013
2013
Elevated glucagon levels and increased hepatic glucagon receptor (GCGR) signaling contribute to hyperglycemia in type 2 diabetes… (More)
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2012
2012
Oxyntomodulin (OXM) is a peptide secreted postprandially from the L-cells of the gut that has a weak affinity for both the… (More)
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2012
2012
Hyperglucagonemia is implicated in the pathophysiology of hyperglycemia. Antagonism of the glucagon receptor (GCGR) thus… (More)
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2012
2012
The glucagon receptor (GCGR) is a member of the class B G protein-coupled receptor family. Activation of GCGR by glucagon leads… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To determine the role of glucagon action in the metabolic phenotype of untreated insulin deficiency. RESEARCH DESIGN… (More)
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2011
2011
Inhibition of glucagon signaling causes hyperglucagonemia and pancreatic α cell hyperplasia in mice. We have recently… (More)
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