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Glioblastoma, IDH- Wildtype
Known as:
Primary Glioblastoma
, Primary Glioblastoma Multiforme
, Primary Glioblastoma, IDH- Wildtype
A glioblastoma that arises de novo. It is more commonly seen in older patients. Mutations in IDH1 or IDH2 genes are not present.
National Institutes of Health
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Related topics
Related topics
19 relations
Anaplasia
Astrocytes
Central Nervous System
EGFR Gene Amplification
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Methods for the detection of cytomegalovirus in glioblastoma cells and tissues.
C. Cobbs
,
Lisa Matlaf
,
L. Harkins
Methods in molecular biology
2014
Corpus ID: 30067198
An increased awareness of the potential oncomodulatory properties of human cytomegalovirus (HCMV) has evolved over the last…
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2013
2013
Identification of Novel Genetic Alterations in Samples of Malignant Glioma Patients
Vedrana P. Milinković
,
Jasna Banković
,
+4 authors
N. Tanić
PLoS ONE
2013
Corpus ID: 1006936
Glioblastoma is the most frequent and malignant human brain tumor. High level of genomic instability detected in glioma cells…
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2012
2012
Functional Differences of miR-125b on the Invasion of Primary Glioblastoma CD133-Negative Cells and CD133-Positive Cells
Lei Shi
,
Yi Wan
,
+7 authors
Y. You
Neuromolecular medicine
2012
Corpus ID: 8389967
MicroRNAs (miRNAs) are small noncoding RNAs whose function as modulators of gene expression is crucial for the proper control of…
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Review
2010
Review
2010
Clinical Significance of Molecular Biomarkers in Glioblastoma
C. Ang
,
M. Guiot
,
A. Ramanakumar
,
David Roberge
,
Petr Kavan
Canadian Journal of Neurological Sciences…
2010
Corpus ID: 6597774
Aim: To review the impact of molecular biomarkers on response to therapy and survival in patients with primary glioblastoma (GBM…
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2009
2009
Elevated levels of IL-1beta in Fanconi anaemia group A patients due to a constitutively active phosphoinositide 3-kinase-Akt pathway are capable of promoting tumour cell proliferation.
A. Ibáñez
,
P. Río
,
J. Casado
,
J. Bueren
,
J. Fernández-Luna
,
C. Pipaón
Biochemical Journal
2009
Corpus ID: 19180054
FA (Fanconi anaemia) is a hereditary disease characterized by congenital malformations, progressive bone marrow failure and an…
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2006
2006
Divergent effects of oncostatin M on astroglioma cells: Influence on cell proliferation, invasion, and expression of matrix metalloproteinases
Shao-Hua Chen
,
G. Gillespie
,
Etty N. Benveniste
Glia
2006
Corpus ID: 43415087
Oncostatin M (OSM), a cytokine of the interleukin‐6 (IL‐6) family, can either promote or inhibit cell growth in various normal…
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2005
2005
Quantitative measurement of deamidation in lens betaB2-crystallin and peptides by direct electrospray injection and fragmentation in a Fourier transform mass spectrometer.
N. Robinson
,
K. Lampi
,
+4 authors
A. B. Robinson
Molecular Vision
2005
Corpus ID: 40675443
PURPOSE Deamidation of lens crystallins and specific deamidation sites have been suggested to be associated with aging and…
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1998
1998
An oncogenic fusion product of the phosphatidylinositol 3-kinase p85β subunit and HUMORF8, a putative deubiquitinating enzyme
J. W. Janssen
,
L. Schleithoff
,
C. Bartram
,
A. Schulz
Oncogene
1998
Corpus ID: 10696188
Peripheral blood cell DNA from a patient with a chronic myeloproliferative disorder was tested in the tumorigenicity assay. Upon…
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Review
1995
Review
1995
Large effect of age on the survival of patients with glioblastoma treated with radiotherapy and brachytherapy boost.
P. Sneed
,
Michael D. Prados
,
+8 authors
P. Gutin
Neurosurgery
1995
Corpus ID: 20659739
A retrospective review was undertaken to study the influence of age on the survival of patients undergoing brachytherapy boost…
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Highly Cited
1995
Highly Cited
1995
Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization.
M. Dreyling
,
S. Bohlander
,
M. Adeyanju
,
O. Olopade
Cancer Research
1995
Corpus ID: 6612143
Deletions of chromosomal band 9p21 have been detected in various tumor types including melanoma, glioma, lung cancer…
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