FAQ

Glioblastoma, IDH- Wildtype

Known as: Primary Glioblastoma, Primary Glioblastoma Multiforme, Primary Glioblastoma, IDH- Wildtype 
A glioblastoma that arises de novo. It is more commonly seen in older patients. Mutations in IDH1 or IDH2 genes are not present.

Topic mentions per year

Topic mentions per year

2002-2017
0246820022017

Related topics

Related topics

16 relations
AnaplasiaAstrocytesCentral Nervous SystemEGFR Gene Amplification
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Glioblastoma, IDH- Wildtype
Nervous system structure
cancer cell
Seizures
Headache
Neuroglia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Spatiotemporal Evolution of the Primary Glioblastoma Genome.
Tumor recurrence following treatment is the major cause of mortality for glioblastoma multiforme (GBM) patients. Thus, insights… (More)
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2015
2015
Identification of a 6-Cytokine Prognostic Signature in Patients with Primary Glioblastoma Harboring M2 Microglia/Macrophage Phenotype Relevance
BACKGROUND Glioblastomas (GBM) are comprised of a heterogeneous population of tumor cells, immune cells, and extracellular matrix… (More)
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2013
2013
Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme.
BACKGROUND Glioblastoma multiforme (GBM) is a highly aggressive brain tumor characterized by massive neovascularization, necrosis… (More)
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2013
2013
Prognostic Relevance of Cytochrome c Oxidase in Primary Glioblastoma Multiforme
Patients with primary glioblastoma multiforme (GBM) have one of the lowest overall survival rates among cancer patients, and… (More)
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2013
2013
Correlation of MicroRNA 132 Up-regulation with an Unfavorable Clinical Outcome in Patients with Primary Glioblastoma Multiforme Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide…
BACKGROUND MicroRNA 132 (miR-132) is dysregulated in a range of human malignancies; however, its role in glioma has not been… (More)
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2012
2012
Correlation of IDH1 Mutation with Clinicopathologic Factors and Prognosis in Primary Glioblastoma: A Report of 118 Patients from China
It has been reported that IDH1 (IDH1R132) mutation was a frequent genomic alteration in grade II and grade III glial tumors but… (More)
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2012
2012
MiR-328 Expression Is Decreased in High-Grade Gliomas and Is Associated with Worse Survival in Primary Glioblastoma
MicroRNAs, a group of small endogenous, noncoding RNAs, are aberrantly expressed in many human cancers and can act as oncogene or… (More)
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2012
2012
Functional Differences of miR-125b on the Invasion of Primary Glioblastoma CD133-Negative Cells and CD133-Positive Cells
MicroRNAs (miRNAs) are small noncoding RNAs whose function as modulators of gene expression is crucial for the proper control of… (More)
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2005
2005
Temozolomide Combined with Irradiation as Postoperative Treatment of Primary Glioblastoma Multiforme
The role of radiochemotherapy in the treatment of primary glioblastoma multiforme is still discussed controversially. To evaluate… (More)
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2005
2005
Radiation Enhances the Invasive Potential of Primary Glioblastoma Cells via Activation of the Rho Signaling Pathway
Glioblastoma multiforme (GBM) is among the most treatment-refractory of all human tumors. Radiation is effective at prolonging… (More)
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