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Glioblastoma, IDH- Wildtype

Known as: Primary Glioblastoma, Primary Glioblastoma Multiforme, Primary Glioblastoma, IDH- Wildtype 
A glioblastoma that arises de novo. It is more commonly seen in older patients. Mutations in IDH1 or IDH2 genes are not present.
National Institutes of Health

Related topics

Related topics

19 relations
AnaplasiaAstrocytesCentral Nervous SystemEGFR Gene Amplification

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Methods for the detection of cytomegalovirus in glioblastoma cells and tissues.
An increased awareness of the potential oncomodulatory properties of human cytomegalovirus (HCMV) has evolved over the last… 
2013
2013
Identification of Novel Genetic Alterations in Samples of Malignant Glioma Patients
Glioblastoma is the most frequent and malignant human brain tumor. High level of genomic instability detected in glioma cells… 
2012
2012
Functional Differences of miR-125b on the Invasion of Primary Glioblastoma CD133-Negative Cells and CD133-Positive Cells
MicroRNAs (miRNAs) are small noncoding RNAs whose function as modulators of gene expression is crucial for the proper control of… 
Review
2010
Review
2010
Clinical Significance of Molecular Biomarkers in Glioblastoma
Aim: To review the impact of molecular biomarkers on response to therapy and survival in patients with primary glioblastoma (GBM… 
2009
2009
Elevated levels of IL-1beta in Fanconi anaemia group A patients due to a constitutively active phosphoinositide 3-kinase-Akt pathway are capable of promoting tumour cell proliferation.
FA (Fanconi anaemia) is a hereditary disease characterized by congenital malformations, progressive bone marrow failure and an… 
2006
2006
Divergent effects of oncostatin M on astroglioma cells: Influence on cell proliferation, invasion, and expression of matrix metalloproteinases
Oncostatin M (OSM), a cytokine of the interleukin‐6 (IL‐6) family, can either promote or inhibit cell growth in various normal… 
2005
2005
Quantitative measurement of deamidation in lens betaB2-crystallin and peptides by direct electrospray injection and fragmentation in a Fourier transform mass spectrometer.
PURPOSE Deamidation of lens crystallins and specific deamidation sites have been suggested to be associated with aging and… 
1998
1998
An oncogenic fusion product of the phosphatidylinositol 3-kinase p85β subunit and HUMORF8, a putative deubiquitinating enzyme
Peripheral blood cell DNA from a patient with a chronic myeloproliferative disorder was tested in the tumorigenicity assay. Upon… 
Review
1995
Review
1995
Large effect of age on the survival of patients with glioblastoma treated with radiotherapy and brachytherapy boost.
A retrospective review was undertaken to study the influence of age on the survival of patients undergoing brachytherapy boost… 
Highly Cited
1995
Highly Cited
1995
Detection of CDKN2 deletions in tumor cell lines and primary glioma by interphase fluorescence in situ hybridization.
Deletions of chromosomal band 9p21 have been detected in various tumor types including melanoma, glioma, lung cancer… 
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