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The blood–brain barrier (BBB) is one of the most complex and selective barriers in the human organism. Its role is to protect the… Expand Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of morbidity and mortality worldwide. The… Expand Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can be metabolized to reactive quinones… Expand Astrocytes have been generally believed to perform mainly homeostatic and supportive functions for neurons in the central nervous… Expand Depression is a chronic, recurring, and serious mood disorder that afflicts up to 20% of the global population. The monoamine… Expand Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They contiguously tile the entire central nervous… Expand For decades, astrocytes have been considered to be non-excitable support cells of the brain. However, this view has changed… Expand Astrocytes are the major glial cell within the central nervous system (CNS) and have a number of important physiological… Expand Glutamate, released at a majority of excitatory synapses in the central nervous system, depolarizes neurons by acting at specific… Expand NEUROTRANSMITTER released from neurons is known to signal to neighbouring neurons and glia1–3 Here we demonstrate an additional… Expand