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EGFR Gene Amplification

Known as: Epidermal Growth Factor Receptor Gene Amplification, c-erbB1 Gene Amplification, EGFR Amplification 
A molecular genetic abnormality indicating the presence of multiple copies of the EGFR gene.
National Institutes of Health

Related topics

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Adenocarcinoma Of EsophagusBarrett's AdenocarcinomaBrain GlioblastomaBreast Carcinoma with Choriocarcinomatous Features

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Association between epidermal growth factor receptor amplification and ADP-ribosylation factor 1 methylation in human glioblastoma
Glioblastoma (GB) is the most frequent and most malignant primary brain tumor in adults. Previously, it has been found that both… 
2016
2016
Relationship Between Cytogenetic Complexity and Peritumoral Edema in High-Grade Astrocytoma
Background The purpose of the study is to reveal the association of cytogenetic compltyexi and peritumoral edema volume (PTEV… 
2016
2016
Epidermal Growth Factor Receptor Gene Amplification in Patients with Advanced-stage NSCLC.
BACKGROUND Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) represent novel, effective tools… 
2015
2015
Concurrence of EGFR amplification and sensitizing mutations indicate a better survival benefit from EGFR-TKI therapy in lung adenocarcinoma patients.
2014
2014
Correlation between EGFR Amplification and the Expression of MicroRNA-200c in Primary Glioblastoma Multiforme
Extensive infiltration of the surrounding healthy brain tissue is a critical feature in glioblastoma. Several miRNAs have been… 
2013
2013
Pyrosequencing for EGFR Mutation Detection: Diagnostic Accuracy and Clinical Implications
EGFR-activating mutations predict responsiveness to EGFR tyrosine kinase inhibitors (TKIs) in non–small cell lung cancer (NSCLC… 
2011
2011
Characterization of Molecular Genetic Alterations in GBMs Highlights a Distinctive Molecular Profile in Young Adults
To evaluate age-related differences in histopathologic and molecular profile of glioblastomas (GBMs) at various age groups, with… 
2011
2011
The role of EGFR amplification in trastuzumab resistance: A correlative analysis of TBCRC003.
528 Background: To identify mechanisms of resistance to trastuzumab (T), we developed and characterized T-resistant HER2+ breast… 
2006
2006
Tissue Microarray Analysis of EGFR Gene Amplification and Gain in Bulgarian Patients with Colorectal Cancer
Colorectal cancer is one of the most common neoplastic diseases and a leading cause of cancer-related deaths. Overexpression of… 
2002
2002
Radiosensitivity and TP53, EGFR Amplification and LOH10 Analysis of Primary Glioma Cell Cultures
Aim: Determination of in-vitro radiosensitivity and genetic alterations of cell cultures derived from human glioma biopsy tissue… 
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