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Genes, Wilms Tumor

Known as: Genes, Wilm, Wilms' Genes, Tumor Genes, Wilms' 
Genes at loci that are involved in the development of WILMS TUMOR. Included are human WT1 at 11p13 and human WT2 (MTACR1) at 11p15.
National Institutes of Health

Related topics

Related topics

9 relations
Beckwith-Wiedemann SyndromeDenys-Drash SyndromeNephroblastomaWAGR Syndrome

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Genes, WT2 Wilms Tumor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Peptide vaccines for myeloid leukaemias.
Review
2006
Review
2006
The modulation of WTI transcription function by cofactors.
Wilms' tumour is a paediatric malignancy of the kidneys that affects one in every 10,000 live births, making it the most common… 
2006
2006
Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenesis.
Highly Cited
2004
Highly Cited
2004
Prognostic classification of relapsing favorable histology Wilms tumor using cDNA microarray expression profiling and support vector machines
Treatment of Wilms tumor has a high success rate, with some 85% of patients achieving long‐term survival. However, late effects… 
2004
2004
Anlaysis of complementary expression profiles following WT1 induction versus repression reveals the cholesterol/fatty acid synthetic pathways as a possible major target of WT1
The Wilms' tumour suppressor gene, WT1, encodes a zinc-finger protein that is mutated in Wilms' tumours and other malignancies… 
Highly Cited
2002
Highly Cited
2002
Identification of a novel WT1‐derived peptide which induces human leucocyte antigen‐A24‐restricted anti‐leukaemia cytotoxic T lymphocytes
Summary. We previously reported the establishment of a Wilms' tumour (WT)1‐derived peptide (CMTWNQMNL)‐specific and human… 
2002
2002
Expression and localization of HGF and met in Wilms' tumours
A number of growth factors and cognate receptors that contribute to normal kidney development have been shown to play roles in… 
Review
1996
Review
1996
Early steps in mammalian sex determination.
Review
1996
Review
1996
Gene targeting in kidney development.
Cancer and development are conceptually related because tumor formation in many cases results from the aberrant expression of a… 
Highly Cited
1994
Highly Cited
1994
Expression of WT1 protein in fetal kidneys and Wilms tumors.
BACKGROUND Wilms' tumors are embryonic kidney neoplasms believed to result from a perturbation in the development of the… 
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