Genes, Suppressor

Known as: Gene, Second-Site Suppressor, Gene, Suppressor, gene suppressor 
Genes that have a suppressor allele or suppressor mutation (SUPPRESSION, GENETIC) which cancels the effect of a previous mutation, enabling the wild… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1960-2017
020040019602017

Papers overview

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Review
2017
Review
2017
Cancer is one of the leading causes of mortality. The neoplastic transformation of normal cells to cancer cells is caused by a… (More)
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Review
2016
Review
2016
Acute myeloid leukemia (AML) is a heterogeneous disorder among hematologic malignancies. Several genetic alterations occur in… (More)
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Review
2016
Review
2016
Tumour-suppressor genes are indispensable for the maintenance of genomic integrity. Recently, several of these genes, including… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that target protein-coding mRNAs at the post… (More)
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Highly Cited
2007
Highly Cited
2007
Adult cancers may derive from stem or early progenitor cells. Epigenetic modulation of gene expression is essential for normal… (More)
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Highly Cited
2003
Highly Cited
2003
The biochemical properties of beclin 1 suggest a role in two fundamentally important cell biological pathways: autophagy and… (More)
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Highly Cited
2003
Highly Cited
2003
The murine Pten prostate cancer model described in this study recapitulates the disease progression seen in humans: initiation of… (More)
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Highly Cited
1999
Highly Cited
1999
Recent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasma… (More)
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Highly Cited
1996
Highly Cited
1996
About 90 percent of human pancreatic carcinomas show allelic loss at chromosome 18q. To identify candidate tumor suppressor genes… (More)
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Highly Cited
1993
Highly Cited
1993
THE tumour-suppressor gene p53 is inactivated in most human malignancies1 either by missense mutations1 or by binding to… (More)
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