Gene regulatory network

Known as: Transcription network, Gene regulatory networks, Gene network 
A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the… (More)
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Topic mentions per year

Topic mentions per year

1969-2017
020040019692017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Gene regulatory networks are perhaps the most important organizational level in the cell where signals from the cell state and… (More)
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Highly Cited
2008
Highly Cited
2008
MOTIVATION In silico modeling of gene regulatory networks has gained some momentum recently due to increased interest in… (More)
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Highly Cited
2007
Highly Cited
2007
Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following… (More)
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Highly Cited
2006
Highly Cited
2006
Elucidating gene regulatory networks is crucial for understanding normal cell physiology and complex pathologic phenotypes… (More)
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Highly Cited
2006
Highly Cited
2006
MOTIVATION Microarray gene expression data has increasingly become the common data source that can provide insights into… (More)
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Highly Cited
2005
Highly Cited
2005
MOTIVATION Signaling pathways are dynamic events that take place over a given period of time. In order to identify these pathways… (More)
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Highly Cited
2005
Highly Cited
2005
The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An… (More)
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Highly Cited
2003
Highly Cited
2003
Boolean networks are a popular model class for capturing the interactions of genes and global dynamical behavior of genetic… (More)
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Highly Cited
2002
Highly Cited
2002
MOTIVATION Our goal is to construct a model for genetic regulatory networks such that the model class: (i) incorporates rule… (More)
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Highly Cited
1999
Highly Cited
1999
As biology enters an era where the genomes of several or ganisms have been completely sequenced the next great challenge is… (More)
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