Ganciclovir

Known as: 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, Nordeoxyguanosine 
A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears… (More)

Topic mentions per year

Topic mentions per year

1973-2017
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Papers overview

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Highly Cited
2007
Highly Cited
2007
Intravenous ganciclovir is the standard treatment for cytomegalovirus disease in solid organ transplant recipients. Oral… (More)
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Highly Cited
2004
Highly Cited
2004
We compared the efficacy and safety of valganciclovir with those of oral ganciclovir in preventing cytomegalovirus (CMV) disease… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE To evaluate the efficacy and safety of ganciclovir therapy in neonates with congenital cytomegalovirus (CMV) disease… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Concerns have been raised about emergence of ganciclovir resistance as a result of the advent of both routine oral… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The intraocular ganciclovir implant is effective for local treatment of cytomegalovirus retinitis in patients with the… (More)
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Highly Cited
1996
Highly Cited
1996
To determine whether cytomegalovirus (CMV) antigenemiaguided ganciclovir treatment may be as effective, may require less… (More)
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Highly Cited
1994
Highly Cited
1994
Protection from cytomegalovirus (CMV) disease in immunocompromised hosts has been shown to correlate with recovery of the host… (More)
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Highly Cited
1993
Highly Cited
1993
OBJECTIVE To study the efficacy and toxicity of ganciclovir prophylaxis given at engraftment to cytomegalovirus (CMV… (More)
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Highly Cited
1992
Highly Cited
1992
Human cytomegalovirus (HCMV) is a major pathogen in immunosuppressed individuals, including patients with acquired immune… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality after allogeneic bone marrow… (More)
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