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Gadd45a protein

Known as: Growth Arrest and DNA-Damage-Inducible, Alpha, GADD45 Gene Product, DNA Damage-Inducible Transcript 1 Protein 
Growth Arrest and DNA-Damage-Inducible, Alpha, encoded by the GADD45A gene, is widely expressed in normal tissues and its expression is increased by… 
National Institutes of Health

Related topics

Related topics

12 relations
ATM Signaling PathwayApoptosisCell Cycle ControlDNA Repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
TLR2-ICAM1-Gadd45α Axis Mediates the Epigenetic Effect of Selenium on DNA Methylation and Gene Expression in Keshan Disease
Keshan disease (KD) is a fatal dilated cardiomyopathy with unknown etiology, and selenium deficiency is considered the main cause… 
2013
2013
Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death.
Highly Cited
2010
Highly Cited
2010
Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat.
Highly Cited
2009
Highly Cited
2009
Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP 'GreenScreen HC' genotoxicity assay.
The GADD45a-GFP (GreenScreen HC) reporter assay detects genotoxic damage in the human lymphoblastoid TK6 cell line and gives… 
Highly Cited
2008
Highly Cited
2008
Different Mechanisms of DEHP‐induced Hepatocellular Adenoma Tumorigenesis in Wild‐type and Pparα‐null Mice
Different Mechanisms of DEHP‐induced Hepatocellular Adenoma Tumorigenesis in Wild‐type and Pparα‐null Mice: Kayoko Takashima, et… 
2008
2008
Assessment of the genotoxicity of S9-generated metabolites using the GreenScreen HC GADD45a-GFP assay.
Genotoxicity can be assessed by monitoring expression of a GADD45a-GFP reporter in the human lymphoblastoid cell line TK6. A flow… 
2006
2006
Soya phytonutrients act on a panel of genes implicated with BRCA1and BRCA2 oncosuppressors in human breast cell lines
Breast cancer is the most common cancer in women and a significant cause of death. Mutations of the oncosuppressor genes BRCA1… 
2005
2005
GADD45A and EPB41 as tumor suppressor genes in meningioma pathogenesis.
2005
2005
Retinoids and Pulmonary Hypertension
Background—Retinoic acid has antimitogenic effects on smooth muscle cells. Studies on the systemic circulation suggest that it… 
2004
2004
Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is a highly malignant tumor that is histologically related to skeletal muscle, yet genetic and molecular… 
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