Skip to search formSkip to main contentSkip to account menu

Gadd45a protein

Known as: Growth Arrest and DNA-Damage-Inducible, Alpha, GADD45 Gene Product, DNA Damage-Inducible Transcript 1 Protein 
Growth Arrest and DNA-Damage-Inducible, Alpha, encoded by the GADD45A gene, is widely expressed in normal tissues and its expression is increased by… 
National Institutes of Health

Related topics

Related topics

12 relations
ATM Signaling PathwayApoptosisCell Cycle ControlDNA Repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression.
2010
2010
A pre-validation transferability study of the GreenScreen HC GADD45a-GFP assay with a metabolic activation system (S9).
Highly Cited
2008
Highly Cited
2008
Different Mechanisms of DEHP‐induced Hepatocellular Adenoma Tumorigenesis in Wild‐type and Pparα‐null Mice
Different Mechanisms of DEHP‐induced Hepatocellular Adenoma Tumorigenesis in Wild‐type and Pparα‐null Mice: Kayoko Takashima, et… 
2008
2008
Assessment of the genotoxicity of S9-generated metabolites using the GreenScreen HC GADD45a-GFP assay.
Genotoxicity can be assessed by monitoring expression of a GADD45a-GFP reporter in the human lymphoblastoid cell line TK6. A flow… 
2008
2008
Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival.
Ionizing radiation (IR) therapy is one of the most commonly used treatments for cancer patients. The responses of tumor cells to… 
Review
2008
Review
2008
GADD45a-GFP GreenScreen HC genotoxicity screening assay
Background: Genetic toxicology is getting very interesting. The International Conference on Harmonisation has drafted new… 
2006
2006
Soya phytonutrients act on a panel of genes implicated with BRCA1and BRCA2 oncosuppressors in human breast cell lines
Breast cancer is the most common cancer in women and a significant cause of death. Mutations of the oncosuppressor genes BRCA1… 
2006
2006
Both the basal transcriptional activity of the GADD45A gene and its enhancement after ionizing irradiation are mediated by AP-1 element.
2004
2004
Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation.
The p53-regulated growth arrest and DNA damage-inducible gene product Gadd45a has been recently identified as a key factor… 
2004
2004
Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is a highly malignant tumor that is histologically related to skeletal muscle, yet genetic and molecular… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)