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Gabexate

Known as: Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester, Ethyl p-hydroxybenzoate 6-guanidinohexanoate, Gabexate [Chemical/Ingredient] 
A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (2)

AnticoagulantsSerine Proteinase Inhibitors

Narrower (3)

FoyGabexate Methanesulfonatecamostat
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice
Background  Bromelain (BR) is a cysteine protease with inhibitory effects on intestinal secretion and inflammation. However, its… 
Highly Cited
2007
Highly Cited
2007
Somatostatin and gabexate for post‐endoscopic retrograde cholangiopancreatography pancreatitis prevention: Meta‐analysis of randomized placebo‐controlled trials
Background and Aim:  Prior studies have suggested the efficacy of somatostatin and gabexate in post‐endoscopic retrograde… 
2006
2006
Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver.
2006
2006
Successful liver transplantation across the ABO incompatibility barrier in 6 cases of biliary atresia.
2002
2002
Pancreatic Protease Inhibition during Shock Attenuates Cell Activation and Peripheral Inflammation
Intestinal ischemia contributes to shock-induced multiple organ failure. Our recent evidence suggests that pancreatic proteases… 
Review
1996
Review
1996
Protease-antiprotease interactions and the rationale for therapeutic protease inhibitors.
A number of pancreatic enzymes have been suggested as the initiating factor for acute pancreatitis. In particular, the… 
1995
1995
Effectiveness of gabexate mesilate in acute pancreatitis
Since the effectiveness of gabexate mesilate in patients with acute pancreatitis is controversial, a metaanalysis of the… 
1986
1986
Protective effect of CR 1409 (cholecystokinin antagonist) on experimental pancreatitis in rats and mice
1982
1982
New approach to regional anticoagulation in hemodialysis using gabexate mesilate (FOY).
Gabexate mesilate (FOY), a synthetic serine proteinase inhibitor, prevented and controlled bleeding during hemodialysis of 3… 
1982
1982
[Effect of secretin and gabexate-mesilate (synthetic protease inhibitor) on serum amylase level after ERCP].
Complication rate of ERCP is about 2%, mortality rate 0,2%. In about 1% acute pancreatitis or recurrency of chronic pancreatitis… 
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