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Gabexate

Known as: Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester, Ethyl p-hydroxybenzoate 6-guanidinohexanoate, Gabexate [Chemical/Ingredient] 
A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Serine proteases such as mast cell tryptase and certain allergens are important in the pathogenesis of allergic… Expand
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2005
2005
Since the effectiveness of gabexate mesilate in patients with acute pancreatitis is controversial, a metaanalysis of the… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES:A continuous 13-h infusion of gabexate starting 30–90 min before endoscopic cholangiopancreatography (ERCP) can reduce… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND ERCP is frequently complicated by pancreatitis. The aims of this study were to assess the efficacy of somatostatin and… Expand
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Highly Cited
2002
Highly Cited
2002
Background. ABO-incompatible liver transplantation is associated with an extremely complicated postoperative course, especially… Expand
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Highly Cited
1998
Highly Cited
1998
Autodigestion of the pancreas, secondary to the activation of digestive enzymes, is the pathogenetic mechanism of acute… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Endoscopic retrograde cholangiopancreatography (ERCP) is associated with elevated levels of pancreatic enzymes and… Expand
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Highly Cited
1993
Highly Cited
1993
SummaryThe authors report the results of a randomized, double-blind multicenter clinical trial on the use of gabexate mesilate vs… Expand
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Highly Cited
1992
Highly Cited
1992
ObjectiveTo determine the effects of disseminated intravascular coagulation (DIC) and headinjury on posttrauma coagulation and… Expand
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