GRM2 gene

Known as: GLUTAMATE RECEPTOR, METABOTROPIC, 2, GRM2, Glutamate Receptor, Metabotropic 2 Gene 
This gene plays a role in the inhibition of adenylate cyclase signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
0519942018

Papers overview

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2014
2014
Metabotropic glutamate (mGlu) receptors play important roles in regulating CNS function and are known to function as obligatory… (More)
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2012
2012
Dopamine, serotonin and glutamate play a role in the pathophysiology of schizophrenia. In the brain a functional crosstalk… (More)
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2011
2011
Dual orthosteric agonists of metabotropic glutamate 2 (mGlu2) and mGlu3 receptors are being developed as novel antipsychotic… (More)
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2011
2011
Group II metabotropic receptors (mGluRs) regulate central synaptic transmission by modulating neurotransmitter release. However… (More)
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2009
2009
BACKGROUND Several lines of evidence implicate abnormalities in glutamate neural transmission in the pathophysiology of mood… (More)
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2006
2006
The metabotropic glutamate receptor 3 (GRM3, mGluR3) is important in regulating synaptic glutamate. Here, we report the existence… (More)
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2006
2006
LY354740 is a potent and selective mGlu2/3 receptor agonist with activity in models of psychiatric disorders (anxiety, psychosis… (More)
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Highly Cited
2004
Highly Cited
2004
(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740) is a potent and selective agonist for group II… (More)
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2001
2001
Metabotropic glutamate receptors (mGluRs) belong to the class of GTP-binding protein coupled receptors and consist of eight… (More)
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2000
2000
The binding properties of [(3)H]-LY354740 were characterized on rat metabotropic glutamate receptors mGlu2 and mGlu3 expressed in… (More)
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