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GRK6 gene

Known as: G protein-coupled receptor kinase 6, G Protein-Coupled Receptor Kinase 6 Gene, GRK6 
This gene is involved in signal transduction.
National Institutes of Health

Related topics

Related topics

6 relations
G Protein-Coupled Receptor SignalingG-protein coupled receptor kinase activityGRK6 protein, humanPhosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
GRK6 phosphorylates IκBα at Ser(32)/Ser(36) and enhances TNF-α-induced inflammation.
2011
2011
Tissue dependent differences in G-protein coupled receptor kinases associated with 5-HT4 receptor desensitization in the rat gastro-intestinal tract.
Highly Cited
2007
Highly Cited
2007
Regulation of Human Melanocortin 1 Receptor Signaling and Trafficking by Thr-308 and Ser-316 and Its Alteration in Variant Alleles Associated with Red Hair and Skin Cancer*
The melanocortin 1 receptor (MC1R), a G protein-coupled receptor (GPCR) positively coupled to adenylyl cyclase, is a key… 
2007
2007
Desensitization of GABAB receptor signaling by formation of protein complexes of GABAB2 subunit with GRK4 or GRK5
We investigated the role of G protein coupled‐receptor kinases (GRKs) in the desensitization of GABAB receptor‐mediated signaling… 
Highly Cited
2005
Highly Cited
2005
Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated…
Attenuation of CRH receptor type 1 (CRH-R1) signaling activity might involve desensitization and uncoupling of CRH-R1 from… 
2003
2003
Endogenous G protein-coupled receptor kinase 6 triggers homologous beta-adrenergic receptor desensitization in primary uterine smooth muscle cells.
We previously reported that G protein-coupled receptor kinase (GRK) may contribute to beta-adrenergic receptor (beta-AR… 
2002
2002
G protein-coupled receptor kinases, beta-arrestin-2 and associated regulatory proteins in the human brain: postmortem changes, effect of age and subcellular distribution.
2001
2001
Concomitant Increase of G Protein-Coupled Receptor Kinase Activity and Uncoupling of β-Adrenergic Receptors in Rat Myometrium at Parturition.
The myometrial β-adrenergic receptor (β-AR)-adenylyl cyclase pathway is markedly desensitized at the end of pregnancy in the rat… 
Highly Cited
2000
Highly Cited
2000
Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors.
Highly Cited
1993
Highly Cited
1993
Identification of additional members of human G-protein-coupled receptor kinase multigene family.
Human neutrophils express several distinct guanine nucleotide binding (G)-protein-coupled receptors that mediate their… 
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