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GRK6 gene

Known as: G protein-coupled receptor kinase 6, G Protein-Coupled Receptor Kinase 6 Gene, GRK6 
This gene is involved in signal transduction.
National Institutes of Health

Related topics

Related topics

6 relations
G Protein-Coupled Receptor SignalingG-protein coupled receptor kinase activityGRK6 protein, humanPhosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Aberrant GRK6 promoter methylation is associated with poor prognosis in hypopharyngeal squamous cell carcinoma.
Hypopharyngeal squamous cell carcinoma (HSCC) is one of the most common head and neck cancers with high invasiveness and poor… 
2015
2015
GRK6 phosphorylates IκBα at Ser(32)/Ser(36) and enhances TNF-α-induced inflammation.
2011
2011
Tissue dependent differences in G-protein coupled receptor kinases associated with 5-HT4 receptor desensitization in the rat gastro-intestinal tract.
Highly Cited
2007
Highly Cited
2007
Regulation of Human Melanocortin 1 Receptor Signaling and Trafficking by Thr-308 and Ser-316 and Its Alteration in Variant Alleles Associated with Red Hair and Skin Cancer*
The melanocortin 1 receptor (MC1R), a G protein-coupled receptor (GPCR) positively coupled to adenylyl cyclase, is a key… 
Highly Cited
2005
Highly Cited
2005
Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated…
Attenuation of CRH receptor type 1 (CRH-R1) signaling activity might involve desensitization and uncoupling of CRH-R1 from… 
2005
2005
Lymphocyte GRK levels as biomarkers in heart failure.
This editorial refers to ‘Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure’† by G… 
2003
2003
Probing the roles of protein kinases in g-protein-coupled receptor desensitization.
For decades we have understood that G-protein-coupled receptors (GPCRs) are crucial links in the relay of information from… 
2001
2001
Concomitant Increase of G Protein-Coupled Receptor Kinase Activity and Uncoupling of β-Adrenergic Receptors in Rat Myometrium at Parturition.
The myometrial β-adrenergic receptor (β-AR)-adenylyl cyclase pathway is markedly desensitized at the end of pregnancy in the rat… 
2001
2001
Concomitant increase of G protein-coupled receptor kinase activity and uncoupling of beta-adrenergic receptors in rat myometrium at parturition.
The myometrial beta-adrenergic receptor (beta-AR)-adenylyl cyclase pathway is markedly desensitized at the end of pregnancy in… 
Highly Cited
2000
Highly Cited
2000
Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors.
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