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GRK1 gene

Known as: G protein-coupled receptor kinase 1, RK, GPRK1 
This gene is involved in sensory transduction necessary for vision.
National Institutes of Health

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GRK1 wt Allele
PhosphorylationRHOK protein, humanSerine/Threonine PhosphorylationSignal Transduction

Papers overview

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2015
2015
The retinal phenotype of Grk1−/− is compromised by a Crb1rd8 mutation
Purpose Well-established laboratory mouse lines are important in creating genetically engineered knockout mouse models; however… 
2014
2014
Unc119 gene deletion partially rescues the GRK1 transport defect of Pde6d (- /-) cones.
PrBP/δ, encoded by the Pde6d gene, is an isoprenyl-binding protein that regulates trafficking of isoprenylated proteins, such as… 
2013
2013
Combined rod and cone transduction by adeno-associated virus 2/8.
Abstract Gene transfer to both cone and rod photoreceptors (PRs) is essential for gene therapy of inherited retinal degenerations… 
2012
2012
Regulation of the methylation status of G protein-coupled receptor kinase 1 (rhodopsin kinase).
2009
2009
A novel mutation in GRK1 causes Oguchi disease in a consanguineous Pakistani family
Purpose The purpose of this study was to identify the underlying molecular genetic defect in a large consanguineous Pakistani… 
2008
2008
Amino Acid Residues in GRK1/GRK7 Responsible for Interaction with S‐Modulin/Recoverin †
GRK1 is a visual pigment kinase in rods and is essential for inactivation of light‐activated rhodopsin. The GRK1 activity is… 
2004
2004
Identification of Epstein-Barr Virus RK-BARF0-Interacting Proteins and Characterization of Expression Pattern
ABSTRACT The Epstein-Barr virus (EBV) BamHI A transcripts are a family of transcripts that are differentially spliced and can be… 
2002
2002
Human substance P receptor undergoes agonist‐dependent phosphorylation by G protein‐coupled receptor kinase 5 in vitro
1998
1998
Mapping the Root-Knot Nematode Resistance Gene (Rk) in Tobacco with RAPD Markers.
Random amplified polymorphic DNA (RAPD) analysis was conducted to map the Rk gene in tobacco which conditions resistance to races… 
1996
1996
Characterization and chromosomal localization of the gene for human rhodopsin kinase.
G-protein-dependent receptor kinases (GRKs) play a key role in the adaptation of receptors to persistent stimuli. In rod… 
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