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GRK1 gene

Known as: G protein-coupled receptor kinase 1, RK, GPRK1 
This gene is involved in sensory transduction necessary for vision.
National Institutes of Health

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GRK1 wt Allele
PhosphorylationRHOK protein, humanSerine/Threonine PhosphorylationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A novel GRK1 mutation in an Italian patient with Oguchi disease
Oguchi disease is a rare autosomal recessive, non-progressive retinal disorder, first described in the Japanese population. It… 
2015
2015
The retinal phenotype of Grk1−/− is compromised by a Crb1rd8 mutation
Purpose Well-established laboratory mouse lines are important in creating genetically engineered knockout mouse models; however… 
2014
2014
Unc119 gene deletion partially rescues the GRK1 transport defect of Pde6d (- /-) cones.
PrBP/δ, encoded by the Pde6d gene, is an isoprenyl-binding protein that regulates trafficking of isoprenylated proteins, such as… 
2012
2012
Regulation of the methylation status of G protein-coupled receptor kinase 1 (rhodopsin kinase).
2011
2011
Expression Of GRK1 And GRK7 In Zebrafish Cones
2009
2009
A novel mutation in GRK1 causes Oguchi disease in a consanguineous Pakistani family
Purpose The purpose of this study was to identify the underlying molecular genetic defect in a large consanguineous Pakistani… 
2008
2008
Amino Acid Residues in GRK1/GRK7 Responsible for Interaction with S‐Modulin/Recoverin †
GRK1 is a visual pigment kinase in rods and is essential for inactivation of light‐activated rhodopsin. The GRK1 activity is… 
2005
2005
Isolation and characterization of visual pigment kinase-related genes in carp retina : Polyphyly in GRK 1 subtypes , GRK 1 A and 1 B
Vertebrate photoreceptor cells are morphologically classified into two types: rods and cones. Rods contribute to scotopic vision… 
2002
2002
Human substance P receptor undergoes agonist‐dependent phosphorylation by G protein‐coupled receptor kinase 5 in vitro
1996
1996
Characterization and chromosomal localization of the gene for human rhodopsin kinase.
G-protein-dependent receptor kinases (GRKs) play a key role in the adaptation of receptors to persistent stimuli. In rod… 
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