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GRIN2B protein, human
Known as:
N-Methyl-D-Aspartate Receptor Subunit 2B
, NMDAR2B
, hNR3
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Glutamate receptor ionotropic, NMDA 2B (1484 aa, ~166 kDa) is encoded by the human GRIN2B gene. This protein plays a role in both calcium transport…
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National Institutes of Health
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Related topics
Related topics
24 relations
Alzheimer's Disease Pathway KEGG
Cellular Membrane
ERBB4 Signaling Pathway
GRIN2B gene
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Broader (1)
NMDA receptor 2B
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation
Wei Lü
,
Juan Du
,
A. Goehring
,
E. Gouaux
Science
2017
Corpus ID: 31654346
Added complexity in an asymmetric receptor N-methyl-d-aspartate receptors (NMDARs) are heterotetrameric ion channels that…
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Highly Cited
2014
Highly Cited
2014
GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine
Oliver H. Miller
,
Lingling Yang
,
+4 authors
B. Hall
eLife
2014
Corpus ID: 191930
A single, low dose of the NMDA receptor antagonist ketamine produces rapid antidepressant actions in treatment-resistant…
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Highly Cited
2013
Highly Cited
2013
Double Dissociation of the Requirement for GluN2B- and GluN2A-Containing NMDA Receptors in the Destabilization and Restabilization of a Reconsolidating Memory
A. Milton
,
E. Merlo
,
P. Ratano
,
B. L. Gregory
,
Jessica K Dumbreck
,
B. Everitt
Journal of Neuroscience
2013
Corpus ID: 22825466
Signaling at NMDA receptors (NMDARs) is known to be important for memory reconsolidation, but while most studies show that NMDAR…
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Highly Cited
2012
Highly Cited
2012
NMDA GluN2A and GluN2B receptors play separate roles in the induction of LTP and LTD in the amygdala and in the acquisition and extinction of conditioned fear
Gemma L. Dalton
,
D. Wu
,
Y. T. Wang
,
S. Floresco
,
A. Phillips
Neuropharmacology
2012
Corpus ID: 20217886
Highly Cited
2011
Highly Cited
2011
Subunit Arrangement and Phenylethanolamine Binding in GluN1/GluN2B NMDA Receptors
E. Karakas
,
N. Simorowski
,
Hiro Furukawa
Nature
2011
Corpus ID: 4425507
Since it was discovered that the anti-hypertensive agent ifenprodil has neuroprotective activity through its effects on NMDA (N…
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Highly Cited
2005
Highly Cited
2005
Multivalent Interactions of Calcium/Calmodulin-dependent Protein Kinase II with the Postsynaptic Density Proteins NR2B, Densin-180, and α-Actinin-2*
Alfred J. Robison
,
M. Bass
,
+4 authors
R. Colbran
Journal of Biological Chemistry
2005
Corpus ID: 30647599
Dendritic calcium/calmodulin-dependent protein kinase II (CaMKII) is dynamically targeted to the synapse. We show that CaMKIIα is…
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Highly Cited
2004
Highly Cited
2004
Synaptic distribution of the NR1, NR2A and NR2B subunits of the N‐methyl‐d‐aspartate receptor in the rat lumbar spinal cord revealed with an antigen‐unmasking technique
G. G. Nagy
,
Masahiko Watanabe
,
M. Fukaya
,
A. Todd
European Journal of Neuroscience
2004
Corpus ID: 29950892
Glutamate is the main excitatory neurotransmitter in the spinal cord and acts on several types of receptor, including N‐methyl‐d…
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Highly Cited
2003
Highly Cited
2003
Pituitary Adenylate Cyclase-activating Polypeptide (PACAP(1–38)) Enhances N-Methyl-d-aspartate Receptor Function and Brain-derived Neurotrophic Factor Expression via RACK1*
R. Yaka
,
D. He
,
Khanhky Phamluong
,
D. Ron
Journal of Biological Chemistry
2003
Corpus ID: 23076291
We recently identified a novel mechanism for modulation of the phosphorylation state and function of theN-methyl-d-aspartate…
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Highly Cited
2001
Highly Cited
2001
Motoneuron-Specific Expression of NR3B, a Novel NMDA-Type Glutamate Receptor Subunit That Works in a Dominant-Negative Manner
M. Nishi
,
H. Hinds
,
Haiping Lu
,
M. Kawata
,
Y. Hayashi
Journal of Neuroscience
2001
Corpus ID: 14932427
We have identified a novel glutamate receptor subunit on the human and mouse genome. Cloning of the mouse cDNA revealed a protein…
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Highly Cited
1996
Highly Cited
1996
Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation.
J. Rostas
,
V. Brent
,
K. Voss
,
M. Errington
,
T. V. P. Bliss
,
J. Gurd
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 7146255
Both serine/threonine and tyrosine phosphorylation of receptor proteins have been implicated in the process of long-term…
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