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GR-43175

Known as: GR 43175, GR43175 
National Institutes of Health

Papers overview

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Highly Cited
1993
Highly Cited
1993
BackgroundSumatriptan (GR43175) is a selective 5-hydroxytryptamine (SHT1) receptor agonist effective in the acute treatment of… Expand
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Highly Cited
1992
Highly Cited
1992
1. Sumatriptan (GR43175) is a selective 5-HT1-receptor agonist effective in the acute treatment of migraine. Vasoactive… Expand
Highly Cited
1991
Highly Cited
1991
Vasoactive neuropeptides, present in unmyelinated C-fibers, can be released from perivascular sensory axons by antidromic… Expand
Highly Cited
1990
Highly Cited
1990
1 We describe the actions of GR43175, a 5‐hydroxytryptamine1 (5‐HT1)‐like receptor agonist, on neurogenically‐mediated plasma… Expand
Highly Cited
1989
Highly Cited
1989
5-Hydroxytryptamine (5-HT) caused contractions of human isolated epicardial coronary arteries which were markedly antagonised by… Expand
Highly Cited
1989
Highly Cited
1989
We describe the identification of a novel drug, GR43175, for the acute treatment of migraine. GR43175 is a tryptamine analogue… Expand
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Highly Cited
1989
Highly Cited
1989
The ability of sumatriptan (GR 43175; 3-[2-dimethylamino]ethyl-N-methyl-1H-indole-5 methane sulphonamide) to interact with 13… Expand
Highly Cited
1989
Highly Cited
1989
1 The aim of this study was to characterize the 5‐hydroxytryptamine (5‐HT) receptor which mediates contraction of canine and… Expand
Highly Cited
1988
Highly Cited
1988
1 We describe the actions of a novel and selective 5‐HT1‐like receptor agonist, GR43175, in a range of isolated tissue… Expand
Highly Cited
1988
Highly Cited
1988
GR43175, a selective 5-HT1-like agonist, was given as an intravenous infusion in an open dose-ranging study to treat 46 attacks… Expand