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GR 205171

Known as: GR-205171, GR205171 
National Institutes of Health

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Broader (1)

vofopitant

Papers overview

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Highly Cited
2007
Highly Cited
2007
Differential effects of dexamethasone, ondansetron and a tachykinin NK1 receptor antagonist (GR205171) on cisplatin-induced changes in behaviour, food intake, pica and gastric function in rats.
Highly Cited
2005
Highly Cited
2005
Cerebral Blood Flow Changes After Treatment of Social Phobia with the Neurokinin-1 Antagonist GR205171, Citalopram, or Placebo
2004
2004
Expression analysis of brain-derived neurotrophic factor (BDNF) mRNA isoforms after chronic and acute antidepressant treatment
Highly Cited
2001
Highly Cited
2001
Comparison of the phenotype of NK1R−/− mice with pharmacological blockade of the substance P (NK 1 ) receptor in assays for antidepressant and anxiolytic drugs
The phenotype of NK1R−/− mice was compared with that of acute pharmacological blockade of the tachykinin NK 1 receptor on… 
Highly Cited
2000
Highly Cited
2000
Pharmacological blockade or genetic deletion of substance P (NK1) receptors attenuates neonatal vocalisation in guinea-pigs and mice
Highly Cited
2000
Highly Cited
2000
Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171 — PET studies in rhesus monkey
Highly Cited
1999
Highly Cited
1999
Antiemetic activity of the NK1 receptor antagonist GR205171 in the treatment of established postoperative nausea and vomiting after major gynaecological surgery.
In this double-blind, randomized, parallel group study, we have investigated the antiemetic activity of the potent and selective… 
1999
1999
Involvement of substance P in the anti‐inflammatory effects of the peripherally selective κ‐opioid asimadoline and the NK1 antagonist GR205171
We have previously shown that kappa‐opioids have antiarthritic properties. In this study, using two differently acting drugs (the… 
Highly Cited
1998
Highly Cited
1998
Reversal of behavioural and electrophysiological correlates of experimental peripheral neuropathy by the NK1 receptor antagonist GR205171 in rats
Highly Cited
1996
Highly Cited
1996
GR205171: A novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity
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