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GPBAR1 gene

Known as: GPCR19, GPR131, GPBAR1 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

G Protein-Coupled Receptor Genes
G-Protein-Coupled Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Roux-en-Y gastrointestinal bypass promotes activation of TGR 5 and peptide YY.
BACKGROUND G protein-coupled bile acid receptor (TGR5) is involved in a number of metabolic diseases. The aim of this study was… 
2019
2019
Dimerization energetics of the G‐protein coupled bile acid receptor TGR5 from all‐atom simulations
We describe the first extensive energetic evaluation of GPCR dimerization on the atomistic level by means of potential of mean… 
2017
2017
An unexpected role for bile acid synthesis in adaptation to low temperature
Enhanced conversion of dietary cholesterol to bile acids through the alternative pathway leads to cold-associated, metabolically… 
2015
2015
Functions of Cholesterol Metabolites.
Cholesterol is a major component of membrane lipids. Thus, adjusting the membrane cholesterol composition is essential for… 
2013
2013
Chemogenomics Approaches to Rationalizing the Mode-of-Action of Traditional Chinese and Ayurvedic Medicines
Traditional Chinese medicine (TCM) and Ayurveda have been used in humans for thousands of years. While the link to a particular… 
2013
2013
Bile Acid Receptor TGR5 Agonism Induces NO Production and Reduces Monocyte Adhesion in Vascular Endothelial Cells
Objective—TGR5 is a G-protein–coupled receptor for bile acids. So far, little is known about the function of TGR5 in vascular… 
2013
2013
Soaping Up Type 2 Diabetes With Bile Acids?
Bile acids (BA) are amphipathic molecules whose physicochemical properties facilitate the solubilization of biliary cholesterol… 
2012
2012
Diabetes: A closer look at the mechanisms of action of colesevelam in humans
the clearance of glucose by tissues in the fasting state and also during a meal, but had no effect on glucose absorption,” say… 
2011
2011
Abnormalities of lipid metabolism, gallstone disease and gallbladder function
Abstract Gallstone disease is highly prevalent with a complex and multifactorial pathogenesis. Gallstones are closely related to… 
2008
2008
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5
Bile acids regulate nongenomic actions through the activation of TGR5, a membrane receptor that is G protein-coupled to the… 
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