GNB3 gene

Known as: G protein subunit beta 3, GUANINE NUCLEOTIDE-BINDING PROTEIN, BETA-3, GNB3 
This gene is plays a role in signal transduction. It is associated with both hypertension and obesity.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Heterotrimeric guanine-binding proteins (G proteins) transmit signals from the cell surface to intracellular signal cascades. The… (More)
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2009
2009
The C825T single nucleotide polymorphism (SNP) in the guanine nucleotide-binding protein, beta polypeptide 3 ( GNB3) gene gives… (More)
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2005
2005
To date, the human G-protein beta 3 subunit (GNB3) gene and some of its variants represent some of the best examples of genetic… (More)
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2003
2003
BACKGROUND Sibutramine, a centrally acting noradrenaline and serotonin re-uptake inhibitor, enhances satiety and is frequently… (More)
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2002
2002
The 825T-allele of the gene GNB3 encoding the G protein beta3 subunit is associated with hypertension and obesity, and identifies… (More)
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2001
2001
OBJECTIVE A polymorphism at position 825(C-->T) of the G protein beta3 (GNB3) gene was found to be associated with enhanced… (More)
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2001
2001
The C825T polymorphism of the gene encoding the G-protein beta(3) subunit (GNB3) is associated with increased intracellular… (More)
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2000
2000
In polygenetic disorders, such as ischemic heart disease, the investigation of gene-gene interactions rather than determination… (More)
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Highly Cited
1999
Highly Cited
1999
The GNB3 825T allele encodes a product that has enhanced activation of heterotrimeric G proteins in vitro and could play a role… (More)
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Highly Cited
1998
Highly Cited
1998
-Essential hypertensives display enhanced signal transduction through pertussis toxin-sensitive G proteins. The T allele of a… (More)
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