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GNB3 gene

Known as: G protein subunit beta 3, GUANINE NUCLEOTIDE-BINDING PROTEIN, BETA-3, GNB3 
This gene is plays a role in signal transduction. It is associated with both hypertension and obesity.
National Institutes of Health

Related topics

Related topics

7 relations
Environment-to-Cell CommunicationG Protein-Coupled Receptor SignalingGNB3 proteinGTP Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: results of A-HeFT.
2009
2009
Gastroesophageal Reflux Disease Is Associated With the C825T Polymorphism in the G-Protein β3 Subunit Gene (GNB3)
OBJECTIVES:Visceral hypersensitivity is involved in the etiology of reflux symptoms. Familial clustering and twin studies… 
2008
2008
Effects of the C825T polymorphism of the GNB3 gene on body adiposity and blood pressure in fertile and menopausal women: a population-based study
Objectives The 825T allele of the GNB3 gene is implicated in adipose distribution, predisposing to obesity and hypertension… 
2007
2007
Gene–environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities Study
Objective:The purpose of this study was to investigate the interaction between the G-protein beta-3 (GNB3) 825C>T polymorphism… 
2006
2006
Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression
SummaryWe studied the association between tryptophan hydroxylase 1 (TPH1) A218C and G-protein beta-3 subunit (GNB3) C825T… 
2003
2003
Cooperative effect of GNB3 825C>T and GPIIIa PI(A) polymorphisms in enhanced platelet aggregation.
Highly Cited
2002
Highly Cited
2002
Identification and ethnic distribution of major haplotypes in the gene GNB3 encoding the G-protein beta3 subunit.
The 825T-allele of the gene GNB3 encoding the G protein beta3 subunit is associated with hypertension and obesity, and identifies… 
2001
2001
G-Protein &bgr;3 Subunit Gene (GNB3) 825T Allele Is Associated With Enhanced Renal Perfusion in Early Hypertension
The C825T polymorphism of the gene encoding the G-protein &bgr;3 subunit (GNB3) is associated with increased intracellular signal… 
Highly Cited
2000
Highly Cited
2000
Interaction of the ACE D Allele and the GNB3 825T Allele in Myocardial Infarction
In polygenetic disorders, such as ischemic heart disease, the investigation of gene-gene interactions rather than determination… 
1999
1999
825T allele of the G-protein beta3 subunit gene (GNB3) is associated with impaired left ventricular diastolic filling in essential hypertension.
OBJECTIVE Recently, a novel C825T polymorphism in the gene (GNB3) encoding for the G-protein beta3 subunit was identified. The… 
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