Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression

@article{Anttila2006InteractionBT,
  title={Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression},
  author={Sami Anttila and Kaija Huuhka and Martti J Huuhka and Riikka Rontu and Kari M. Mattila and Esa Veli Juhani Leinonen and Terho Lehtim{\"a}ki},
  journal={Journal of Neural Transmission},
  year={2006},
  volume={114},
  pages={461-468}
}
We studied the association between tryptophan hydroxylase 1 (TPH1) A218C and G-protein beta-3 subunit (GNB3) C825T polymorphisms and treatment response in electroconvulsive therapy (ECT). The sample consisted of 119 patients with major depressive disorder (MDD) and 398 controls. Neither TPH1 nor GNB3 polymorphisms are associated with treatment response. However, subjects carrying TPH1 CC genotype are more likely to belong to the patient sample than to the controls. In female subjects, T-allele… CONTINUE READING

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References

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Showing 1-10 of 53 references

SSRIs antidepressant activity is influenced by G beta 3 variants.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology • 2003
View 7 Excerpts
Highly Influenced

Influence of 5-HTTLPR and TPH variants on illness time course in mood disorders.

Journal of psychiatric research • 2001
View 4 Excerpts
Highly Influenced

Tryptophan hydroxylase gene and major psychoses.

Psychiatry research • 2001
View 3 Excerpts
Highly Influenced

Tryptophan hydroxylase gene associated with paroxetine antidepressant activity.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology • 2001
View 3 Excerpts
Highly Influenced

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