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GATA3 protein, human

Known as: HDR protein, human, GATA-Binding Factor 3, GATA-3 binding protein, human 
Trans-acting T-cell-specific transcription factor GATA-3 (443 aa, ~48 kDa) is encoded by the human GATA3 gene. This protein plays a role in… 
National Institutes of Health

Related topics

Related topics

9 relations
DNA-Binding ProteinsGATA3 geneGenes, RegulatorHomo sapiens

Broader (1)

GATA3 Transcription Factor

Papers overview

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Highly Cited
2006
Highly Cited
2006
Distinct Responses of Lung and Spleen Dendritic Cells to the TLR9 Agonist CpG Oligodeoxynucleotide1
Dendritic cells (DCs) sense various components of invading pathogens via pattern recognition receptors such as TLRs. CpG… 
Highly Cited
2005
Highly Cited
2005
mRNA Quantification of T-bet, GATA-3, IFN-γ, and IL-4 Shows a Defective Th1 Immune Response in the Peripheral Blood from Rheumatoid Arthritis Patients: Link with Disease Activity
A T helper (Th)1 cytokine profile is predominant in the inflamed synovium of rheumatoid arthritis (RA). Since the situation in… 
Review
2004
Review
2004
T cell directives for transcriptional regulation in asthma
Allergic asthma frequently starts in childhood, and environmental factors such as viruses, allergens and occupational exposure… 
Highly Cited
2003
Highly Cited
2003
Genetic Reprogramming of Primary Human T Cells Reveals Functional Plasticity in Th Cell Differentiation
Activation of naive T cells through the TCR and cytokine signals directs their differentiation into effector or memory subsets… 
Highly Cited
2002
Highly Cited
2002
Cutting Edge: Identification of an Alternative GATA-3 Promoter Directing Tissue-Specific Gene Expression in Mouse and Human1
The GATA family of transcription factors regulates development of multiple tissues. Several GATA factors have two promoters… 
Highly Cited
2002
Highly Cited
2002
Interleukin-13 Gene Expression Is Regulated by GATA-3 in T Cells
Using a transgenic approach, we studied the role of GATA-3 in T cells. As previously shown, enforced GATA-3 expression in… 
Highly Cited
2001
Highly Cited
2001
TH2 cytokine-associated transcription factors in atopic and nonatopic asthma: evidence for differential signal transducer and activator of transcription 6 expression.
BACKGROUND The expression of IL-4 and IL-5 is increased in patients with atopic asthma compared with control subjects and… 
Highly Cited
1999
Highly Cited
1999
T-cell Expression of the Human GATA-3 Gene Is Regulated by a Non-lineage-specific Silencer*
The GATA-3 transcription factor is required for development of the T-cell lineage and Th2 cytokine gene expression in CD4 T-cells… 
Review
1993
Review
1993
Transcriptional regulation of T cell receptor genes.
The diverse lineages of the mammalian hematopoietic system including both B and T lymphocytes are derived from a single… 
Highly Cited
1993
Highly Cited
1993
Expression of the chicken GATA factor family during early erythroid development and differentiation.
The DNA motif WGATAR has been identified within transcriptional regulatory domains of globin and other erythroid-specific genes… 
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