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GAG Gene

Known as: Genes, gag, Gene, gag, GAG 
DNA sequences that form the coding region for proteins associated with the viral core in retroviruses. gag is short for group-specific antigen.
National Institutes of Health

Related topics

Related topics

4 relations
RetroviridaeVirus Physiological Phenomenaaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2009
Highly Cited
2009
Structure and assembly of immature HIV
The major structural components of HIV are synthesized as a 55-kDa polyprotein, Gag. Particle formation is driven by the self… 
Highly Cited
2001
Highly Cited
2001
Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55Gag
Ubiquitination appears to be involved in virus particle release from infected cells. Free ubiquitin (Ub), as well as Ub… 
Highly Cited
2000
Highly Cited
2000
NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition.
The RNA genome of the human immunodeficiency virus type-1 (HIV-1) contains a approximately 120 nucleotide Psi-packaging signal… 
Highly Cited
2000
Highly Cited
2000
A role for ubiquitin ligase recruitment in retrovirus release.
Retroviral Gag polyproteins have specific regions, commonly referred to as late assembly (L) domains, which are required for the… 
Highly Cited
1997
Highly Cited
1997
HIV‐1 infection of non‐dividing cells: evidence that the amino‐terminal basic region of the viral matrix protein is important for Gag processing but not for post‐entry nuclear import
Human immunodeficiency virus type‐1 (HIV‐1) is able to infect non‐dividing cells such as tissue macrophages productively because… 
Highly Cited
1994
Highly Cited
1994
Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids
Retroviral Gag proteins are targeted to the plasma membrane, where they play the central role in virion formation. Several… 
Highly Cited
1992
Highly Cited
1992
The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions
Accumulating evidence suggests that the matrix (MA) protein of retroviruses plays a key role in virus assembly by directing the… 
Highly Cited
1988
Highly Cited
1988
The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag…
Seven human immunodeficiency virus gag polypeptides were identified in the purified virus and in infected CD4+ lymphocytes by… 
Highly Cited
1983
Highly Cited
1983
Nucleotide sequence of rous sarcoma virus
Highly Cited
1980
Highly Cited
1980
Design of an artificial skin. II. Control of chemical composition.
Detailed methodology is described for the reproducible preparation of collagen--glycosaminoglycan (GAG) membranes with known… 
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