GADD45A gene

Known as: GADD45, GROWTH ARREST- AND DNA DAMAGE-INDUCIBLE GENE GADD45, ALPHA, Growth Arrest and DNA-Damage-Inducible, Alpha Gene 
This gene plays a role in signal transduction and is induced in response to environmental stress. It is involved in apoptosis, DNA repair and… (More)
National Institutes of Health

Papers overview

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2010
2010
Curcumin, a phenolic compound isolated from the plant Curcuma longa (Linn), is ingested every day in the Indian subcontinent and… (More)
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2009
2009
The GADD45a-GFP (GreenScreen HC) reporter assay detects genotoxic damage in the human lymphoblastoid TK6 cell line and gives… (More)
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Highly Cited
2006
Highly Cited
2006
Gadd45a, Gadd45b, and Gadd45g (Gadd45/MyD118/CR6) are genes that are rapidly induced by genotoxic stress and have been implicated… (More)
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2005
2005
Treatment of the breast cancer cell line, MDAMB468 with the DNA methylation inhibitor, 5-azacytidine (5-AzaC) results in growth… (More)
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2005
2005
Gadd45a, a p53- and BRCA1-regulated stress protein, has been implicated in the maintenance of genomic fidelity, probably through… (More)
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Highly Cited
2005
Highly Cited
2005
The CpG island of GADD45G was identified as a target sequence during the identification of hypermethylated genes using… (More)
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2005
2005
Deletions of 1p occur in approximately 30% of meningiomas. Based on loss of heterozygosity (LOH) analysis, two regions on 1p have… (More)
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2001
2001
Gadd45a is an 18-kDa acidic protein that is induced by genotoxic and certain other cellular stresses. The exact function of this… (More)
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2001
2001
Mice lacking the Gadd45a gene are susceptible to ionizing radiation-induced tumors. Increased levels of Gadd45a transcript and… (More)
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Review
1994
Review
1994
By genetically manipulating hematopoietic cells of the myeloid lineage, including both normal cells and differentiation inducible… (More)
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