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GADD45A gene

Known as: GADD45, GROWTH ARREST- AND DNA DAMAGE-INDUCIBLE GENE GADD45, ALPHA, Growth Arrest and DNA-Damage-Inducible, Alpha Gene 
This gene plays a role in signal transduction and is induced in response to environmental stress. It is involved in apoptosis, DNA repair and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Gadd45a, Gadd45b, and Gadd45g (Gadd45/MyD118/CR6) are genes that are rapidly induced by genotoxic stress and have been implicated… Expand
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Highly Cited
2005
Highly Cited
2005
The CpG island of GADD45G was identified as a target sequence during the identification of hypermethylated genes using… Expand
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Highly Cited
2003
Highly Cited
2003
1,25-Dihydroxyvitamin D3 suppresses the growth of multiple human cancer cell lines by inhibiting cell cycle progression and… Expand
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Highly Cited
2003
Highly Cited
2003
Abstract— Peroxisome proliferator-activated receptor (PPAR) &ggr; is activated by thiazolidinediones (TZDs), widely used as… Expand
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Highly Cited
2002
Highly Cited
2002
BRCA1, a breast and ovarian cancer susceptibility gene, has been implicated in gene regulation. Previous studies demonstrate that… Expand
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Review
2000
Review
2000
gadd45 is a p53-regulated growth arrest and DNA-damage-inducible gene that is also regulated in a p53-independent manner. Whether… Expand
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Highly Cited
1999
Highly Cited
1999
Recently Gadd45, a p53-regulated stress protein, has been implicated in the activation of a G2/M checkpoint after damage by UV… Expand
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Highly Cited
1999
Highly Cited
1999
The breast cancer susceptibility gene BRCA1 encodes a protein implicated in the cellular response to DNA damage, with postulated… Expand
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Highly Cited
1998
Highly Cited
1998
We report here that the expression of virtually all proposed c-Myc target genes is unchanged in cells containing a homozygous… Expand
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Highly Cited
1995
Highly Cited
1995
GADD45 was originally identified as a cDNA clone induced by growth arrest and DNA damage. We show that Gadd45 is a nuclear… Expand
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