Ftorafur

Even though conventional pharmacotherapy has been demonstrated to display very efficient activity against a wide variety of… Expand

In the present work, a method is described to prepare polymeric colloidal nanospheres, consisting of poly(ethyl-2-cyanoacrylate… Expand

S-1 is an oral formulation of ftorafur (FT), oxonic acid and 5-chloro-2,4-dihydroxypyridine (CDHP) at a molar ratio of 1:0.4:1… Expand

1. Painstaking progress in drug development is well illustrated by 5-fluorouracil (5FU), originally designed 40 years ago as a… Expand

Abstract A phase I and pharmacokinetic study of oral uracil, ftorafur, and leucovorin was performed in patients with advanced… Expand

BACKGROUND UFT is a fixed-ratio combination of uracil and Ftorafur, a prodrug that is absorbed orally and metabolized in vivo to… Expand

Based on the overall results of a UFT phase II study made in 104 institutions in Japan from April of 1979 to September of 1980… Expand

A group of 243 patients with gastric cancer was subjected to a prospective randomized trial of adjuvant chemotherapy after… Expand

One hundred patients with non-small cell lung cancer were entered into a randomized evaluation of two schedules of doxorubicin… Expand

Ftorafur, an active tumor drug, is less toxic than 5-fluorouracil and was most effective in cancer of the breast and cancer of… Expand