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Ftorafur

National Institutes of Health

Papers overview

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2007
2007
In the present work, a method is described to prepare polymeric colloidal nanospheres, consisting of poly(ethyl-2-cyanoacrylate… Expand
Review
2003
Review
2003
OBJECTIVES To evaluate the clinical and cost-effectiveness of capecitabine and tegafur with uracil (UFT/LV) as first-line… Expand
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Review
1998
Review
1998
1. Painstaking progress in drug development is well illustrated by 5‐fluorouracil (5FU), originally designed 40 years ago as a… Expand
Highly Cited
1996
Highly Cited
1996
Abstract A phase I and pharmacokinetic study of oral uracil, ftorafur, and leucovorin was performed in patients with advanced… Expand
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Highly Cited
1995
Highly Cited
1995
Background. UFT is a fixed‐ratio combination of uracil and Ftorafur, a prodrug that is absorbed orally and metabolized in vivo to… Expand
Highly Cited
1992
Highly Cited
1992
Two hundred patients with node positive stage II breast cancer were randomised to four groups after radical mastectomy and… Expand
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Highly Cited
1984
Highly Cited
1984
A group of 243 patients with gastric cancer was subjected to a prospective randomized trial of adjuvant chemotherapy after… Expand
Highly Cited
1978
Highly Cited
1978
The pharmacology of high-dose 1-(tetrahydro-2-furanyl)-5-fluorouracil (FT) has been studied by radiochemical and chromatographic… Expand
Highly Cited
1976
Highly Cited
1976
Ftorafur, a possible sustained-release formulation of 5-fluorouracil, was administered to 27 patients with metastatic cancers… Expand
Highly Cited
1972
Highly Cited
1972
Ftorafur, an active tumor drug, is less toxic than 5‐fluorouracil and was most effective in cancer of the breast and cancer of… Expand