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In the present work, a method is described to prepare polymeric colloidal nanospheres, consisting of poly(ethyl-2-cyanoacrylate… Expand OBJECTIVES
To evaluate the clinical and cost-effectiveness of capecitabine and tegafur with uracil (UFT/LV) as first-line… Expand 1. Painstaking progress in drug development is well illustrated by 5‐fluorouracil (5FU), originally designed 40 years ago as a… Expand Abstract A phase I and pharmacokinetic study of oral uracil, ftorafur, and leucovorin was performed in patients with advanced… Expand Background. UFT is a fixed‐ratio combination of uracil and Ftorafur, a prodrug that is absorbed orally and metabolized in vivo to… Expand Two hundred patients with node positive stage II breast cancer were randomised to four groups after radical mastectomy and… Expand A group of 243 patients with gastric cancer was subjected to a prospective randomized trial of adjuvant chemotherapy after… Expand The pharmacology of high-dose 1-(tetrahydro-2-furanyl)-5-fluorouracil (FT) has been studied by radiochemical and chromatographic… Expand Ftorafur, a possible sustained-release formulation of 5-fluorouracil, was administered to 27 patients with metastatic cancers… Expand Ftorafur, an active tumor drug, is less toxic than 5‐fluorouracil and was most effective in cancer of the breast and cancer of… Expand