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Tegafur
Known as:
1-(Tetrahydro-2-furanyl)-5-fluorouracil
, Tegafur [Chemical/Ingredient]
, 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
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A congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil in the…
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National Institutes of Health
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Related topics
Related topics
37 relations
Narrower (24)
3-FT
ACFM protocol
BMFt protocol
COPU protocol
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Broader (1)
Antimetabolites, Antineoplastic
In Blood
NCIt Antineoplastic Agent Terminology
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
The subrenal capsule assay in selecting chemotherapy for ovarian cancer: a prospective randomized trial.
J. Mäenpää
,
E. Heinonen
,
+16 authors
M. Väyrynen
Gynecologic Oncology
1995
Corpus ID: 21912248
In order to find out whether the response rate and survival in epithelial ovarian cancer can be improved by aid of sensitivity…
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1985
1985
Antitumor activity of a new fluoropyrimidine derivative, 5'-deoxy-5-fluorouridine, against murine and human experimental tumors.
Shuichi Fujimoto
,
Yi Wang
,
Katsuhiro Inoue
,
Makoto Ogawa
Japanese journal of cancer research : Gann
1985
Corpus ID: 45891194
5'-Deoxy-5-fluorouridine (5'-DFUR) was evaluated for antitumor activity against four murine tumors (L1210 leukemia, P388 leukemia…
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1985
1985
Relevance of the pharmacology of oral tegafur to its use as a 5-FU pro-drug.
J. Byfield
,
C. L. Hornbeck
,
S. Frankel
,
T. Sharp
,
J. C. Griffiths
Cancer treatment reports
1985
Corpus ID: 26043883
We have studied the pharmacology of iv and oral tegafur (FT) and compared the results with similar studies using continuously…
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1983
1983
Phase I evaluation of oral tegafur.
A. Bedikian
,
G. Bodey
,
M. Valdivieso
,
Michael A. Burgess
Cancer treatment reports
1983
Corpus ID: 25423116
A phase I clinical study of tegafur (ftorafur) was conducted in 29 patients with various advanced solid tumors. To evaluate its…
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1983
1983
Plasma levels of tegafur following implantation of polycarbonate pellets containing tegafur or FD-1 into rats.
T. Kawaguchi
,
M. Nakano
,
Kazuhiko Juni
,
S. Inoue
,
Yasuhiko Yoshida
Chemical and pharmaceutical bulletin
1983
Corpus ID: 45265047
The possible use of poly (ethylene carbonate) and poly (propylene carbonate) pellets for sustained release of 5-fluorouracil…
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Review
1982
Review
1982
[Clinical survey on cardiotoxicity of tegafur (FT-207)--compilation of a nationwide survey].
K. Kikuchi
,
S. Majima
,
M. Murakami
Gan to kagaku ryoho. Cancer & chemotherapy
1982
Corpus ID: 30762242
To examine FT-207 cardiotoxicity, medical records of 223 cancer patients from 23 institutions throughout Japan were subjected to…
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1978
1978
Photosensitivity due to a fluorouracil derivative.
Takeshi Horio
,
T. Murai
,
Kouichi Ikai
Archives of Dermatology
1978
Corpus ID: 10809156
A photosensitive lichen planus-like eruption developed in a 63-year-old man during postoperative chemotherapy with 1-(2…
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1978
1978
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in Lewis lung carcinoma and B16 melanoma.
M. Iigo
,
A. Hoshi
,
Asako Nakamura
,
K. Kuretani
1978
Corpus ID: 71486116
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil (HCFU) against Lewis lung carcinoma and B16 melanoma by long-term oral…
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1976
1976
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in a variety of experimental tumors.
Akio Hoshi
,
Masaaki Iigo
,
Asako Nakamura
,
Mitsuzi Yoshida
,
Kazuo Kuretani
Gan
1976
Corpus ID: 12270118
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil against various tumors was examined. Therapeutic ratio (ILSmax/ILS30) in L…
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1976
1976
Physical properties of pyrimidine and purine antimetabolites. I. The effects of salts and temperature on the solubility of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil, 6-mercaptopurine, and…
Yoshiko Arakawa
,
Masahiro Nakano
,
Kazuhiko Juni
,
Takaichi Arita
Chemical and pharmaceutical bulletin
1976
Corpus ID: 23353816
The effects of sodium chloride, sodium sulfate, and sodium iodide on the solubility of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5…
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