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Tegafur
Known as:
1-(Tetrahydro-2-furanyl)-5-fluorouracil
, Tegafur [Chemical/Ingredient]
, 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
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A congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil in the…
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National Institutes of Health
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Related topics
Related topics
37 relations
Narrower (24)
3-FT
ACFM protocol
BMFt protocol
COPU protocol
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Broader (1)
Antimetabolites, Antineoplastic
In Blood
NCIt Antineoplastic Agent Terminology
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
A Prospective Randomized Evaluation of a Compound of Tegafur and Uracil as an Adjuvant Chemotherapy for Hepatocellular Carcinoma Treated with Transcatheter Arterial Chemoembolization
K. Ikeda
,
S. Saitoh
,
+4 authors
H. Kumada
American Journal of Clinical Oncology
1995
Corpus ID: 25181334
A prospective randomized trial was conducted to evaluate the efficacy of long-term oral administration of low-dose tegafur…
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1995
1995
The subrenal capsule assay in selecting chemotherapy for ovarian cancer: a prospective randomized trial.
J. Mäenpää
,
E. Heinonen
,
+16 authors
M. Väyrynen
Gynecologic Oncology
1995
Corpus ID: 21912248
In order to find out whether the response rate and survival in epithelial ovarian cancer can be improved by aid of sensitivity…
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1984
1984
Effect of coadministration of uracil on the toxicity of tegafur.
J. Yamamoto
,
A. Haruno
,
+4 authors
K. Morita
Journal of Pharmacy and Science
1984
Corpus ID: 40979298
The cardiotoxic and neurotoxic effects of tegafur, an anticancer agent, were compared with those of uracil plus tegafur (4:1 mol…
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Highly Cited
1983
Highly Cited
1983
Phase I-II studies of oral tegafur (ftorafur).
F. Ansfield
,
G. J. Kallas
,
J. P. Singson
Journal of Clinical Oncology
1983
Corpus ID: 23164536
A total of 65 patients with advanced colorectal or breast cancer were given oral tegafur in the phase I study. Of these, 28…
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1983
1983
Phase I evaluation of oral tegafur.
A. Bedikian
,
G. Bodey
,
M. Valdivieso
,
M. Burgess
Cancer treatment reports
1983
Corpus ID: 25423116
A phase I clinical study of tegafur (ftorafur) was conducted in 29 patients with various advanced solid tumors. To evaluate its…
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1980
1980
Effect of coadministration of thymine or thymidine on the antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil.
S. Fujii
,
S. Kitano
,
+4 authors
T. Shirasaka
Gan
1980
Corpus ID: 19925431
The antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) on sarcoma was enhanced by oral coadministration of…
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1978
1978
Photosensitivity due to a fluorouracil derivative.
T. Horio
,
T. Murai
,
K. Ikai
Archives of Dermatology
1978
Corpus ID: 10809156
A photosensitive lichen planus-like eruption developed in a 63-year-old man during postoperative chemotherapy with 1-(2…
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1978
1978
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in Lewis lung carcinoma and B16 melanoma.
M. Iigo
,
A. Hoshi
,
A. Nakamura
,
K. Kuretani
1978
Corpus ID: 71486116
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil (HCFU) against Lewis lung carcinoma and B16 melanoma by long-term oral…
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1976
1976
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in a variety of experimental tumors.
A. Hoshi
,
M. Iigo
,
A. Nakamura
,
M. Yoshida
,
K. Kuretani
Gan
1976
Corpus ID: 12270118
Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil against various tumors was examined. Therapeutic ratio (ILSmax/ILS30) in L…
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1976
1976
Physical properties of pyrimidine and purine antimetabolites. I. The effects of salts and temperature on the solubility of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5-fluorouracil, 6-mercaptopurine, and…
Y. Arakawa
,
M. Nakano
,
K. Juni
,
T. Arita
Chemical and pharmaceutical bulletin
1976
Corpus ID: 23353816
The effects of sodium chloride, sodium sulfate, and sodium iodide on the solubility of 5-fluorouracil, 1-(2-tetrahydrofuryl)-5…
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