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Forkhead Transcription Factors

Known as: Transcription Factors, Forkhead, Fox Transcription Factors, Transcription Factors, Fox 
A subclass of winged helix DNA-binding proteins that share homology with their founding member fork head protein, Drosophila.
National Institutes of Health

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34 relations

Narrower (25)

FOXG1B protein, humanFOXH1 protein, XenopusFOXJ1 protein, ratFOXK1 protein, human
FOXR2 geneIn BloodProcess of secretionagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
FOXO Transcription Factors: Their Clinical Significance and Regulation
Members of the class O of forkhead box transcription factors (FOXO) have important roles in metabolism, cellular proliferation… 
Highly Cited
2013
Highly Cited
2013
DNA-binding specificity changes in the evolution of forkhead transcription factors
The evolution of transcriptional regulatory networks entails the expansion and diversification of transcription factor (TF… 
Highly Cited
2012
Highly Cited
2012
The Yeast Forkhead Transcription Factors Fkh1 and Fkh2 Regulate Lifespan and Stress Response Together with the Anaphase-Promoting Complex
Forkhead box O (FOXO) transcription factors have a conserved function in regulating metazoan lifespan. A key function in this… 
Review
2008
Review
2008
Structure/function relationships underlying regulation of FOXO transcription factors
The FOXO subgroup of forkhead transcription factors plays a central role in cell-cycle control, differentiation, metabolism… 
Highly Cited
2006
Highly Cited
2006
Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells
This study is the first to investigate the anticancer effect of plumbagin in human breast cancer cells. Plumbagin exhibited cell… 
Highly Cited
2005
Highly Cited
2005
The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription.
The FOXO (Forkhead box class O) subgroup of forkhead transcription factors controls the expression of many genes involved in… 
Highly Cited
2004
Highly Cited
2004
Control of Cyclin G2 mRNA Expression by Forkhead Transcription Factors: Novel Mechanism for Cell Cycle Control by Phosphoinositide 3-Kinase and Forkhead
ABSTRACT Cyclin G2 is an unconventional cyclin highly expressed in postmitotic cells. Unlike classical cyclins that promote cell… 
Highly Cited
2002
Highly Cited
2002
A Forkhead Transcription Factor Is Important for True Hyphal as well as Yeast Morphogenesis in Candida albicans
ABSTRACT Candida albicans is an important pathogen of immunocompromised patients which grows with true hyphal, pseudohyphal, and… 
Highly Cited
2000
Highly Cited
2000
Damage Tolerance Protein Mus81 Associates with the FHA1 Domain of Checkpoint Kinase Cds1
ABSTRACT Cds1, a serine/threonine kinase, enforces the S-M checkpoint in the fission yeast Schizosaccharomyces pombe. Cds1 is… 
Highly Cited
1999
Highly Cited
1999
Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt
Akt, a proto-oncogene that encodes a cytosolic serine/threonine kinase, can phosphorylate and modulate the activity of several… 
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