Flecainide

Known as: Flecainida, Flecainidum, Flecaine 
A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
OBJECTIVES This study evaluated the efficacy and safety of flecainide in addition to conventional drug therapy in patients with… (More)
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Highly Cited
2009
Highly Cited
2009
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal inherited arrhythmia syndrome in which drug… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES The purpose of this study was to compare the effect of intravenous flecainide and ajmaline with respect to their… (More)
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Highly Cited
2004
Highly Cited
2004
Users of clinical practice guidelines and other recommendations need to know how much confidence they can place in the… (More)
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Highly Cited
2004
Highly Cited
2004
Axonal degeneration is a major cause of permanent neurological deficit in multiple sclerosis (MS), but no current therapies for… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Defects of the SCN5A gene encoding the cardiac sodium channel are associated with both the LQT3 subtype of long-QT… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND We recently reported that sodium channel block can produce opposite effects on action potential duration (APD) and… (More)
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Highly Cited
1992
Highly Cited
1992
Class Ic antiarrhythmic drugs are effective in the treatment of atrial fibrillation, but their mechanism of action is unknown. In… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS In the Cardiac Arrhythmia Suppression Trial, designed to test the hypothesis that suppression of… (More)
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Highly Cited
1989
Highly Cited
1989
The occurrence of ventricular premature depolarizations in survivors of myocardial infarction is a risk factor for subsequent… (More)
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