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Filamins

Known as: Filamin, Filamins [Chemical/Ingredient] 
A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that occurs in response to resistance… Expand
Highly Cited
2006
Highly Cited
2006
We show that actin filaments, shortened to physiological lengths by gelsolin and cross-linked with recombinant human filamins… Expand
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Review
2006
Review
2006
Filamins are elongated homodimeric proteins that crosslink F-actin. Each monomer chain of filamin comprises an actin-binding… Expand
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Highly Cited
2006
Highly Cited
2006
The ability of adhesion receptors to transmit biochemical signals and mechanical force across cell membranes depends on… Expand
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Review
2004
Review
2004
Filamins were discovered as the first family of non-muscle actin-binding protein. They are lage cytoplasmic proteins that cross… Expand
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Highly Cited
2003
Highly Cited
2003
Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the gene FLNA, is… Expand
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Review
2001
Review
2001
Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin webs and link them to cellular… Expand
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Highly Cited
1999
Highly Cited
1999
The Ras-related small GTPases Rac, Rho, Cdc42, and RalA bind filamin, an actin filament-crosslinking protein that also links… Expand
Highly Cited
1998
Highly Cited
1998
Long-range, directed migration is particularly dramatic in the cerebral cortex, where postmitotic neurons generated deep in the… Expand
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Highly Cited
1990
Highly Cited
1990
Actin-binding protein (ABP-280, nonmuscle filamin) is a ubiquitous dimeric actin cross-linking phosphoprotein of peripheral… Expand
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