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FLNA protein, human

Known as: filamin A, alpha (actin binding protein 280), human, EC 6.3.4.4, Actin Binding Protein 280 
Filamin-A (2647 aa, ~281 kDa) is encoded by the human FLNA gene. This protein is involved in cytoskeletal remodeling.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Filamin A (FLNa) can effect orthogonal branching of F-actin and bind many cellular constituents. FLNa dimeric subunits have N… 
Highly Cited
2006
Highly Cited
2006
FilGAP is a newly recognized filamin A (FLNa)-binding RhoGTPase-activating protein. The GTPase-activating protein (GAP) activity… 
Highly Cited
2006
Highly Cited
2006
Mutations in the human Filamin A (FLNA) gene disrupt neuronal migration to the cerebral cortex and cause cardiovascular defects… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT The transmembrane peptidase prostate-specific membrane antigen (PSMA) is universally upregulated in the vasculature of… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT β-Arrestins (βarr) are multifunctional adaptor proteins that can act as scaffolds for G protein-coupled receptor… 
Highly Cited
2004
Highly Cited
2004
In the developing neocortex, most excitatory neurons are supplied and arranged through radial migration. Because neurons show… 
Highly Cited
2003
Highly Cited
2003
The androgen receptor (AR), a nuclear transcription factor, mediates male sexual differentiation, and its excessive action is… 
Highly Cited
2002
Highly Cited
2002
Although proteins phosphorylated on tyrosine residues can be enriched by immunoprecipitation with anti-phosphotyrosine antibodies… 
Highly Cited
2002
Highly Cited
2002
An absent platelet glycoprotein (GP) Ib-IX receptor results in the Bernard-Soulier syndrome and is characterized by severe… 
Highly Cited
2001
Highly Cited
2001
We have used a yeast two-hybrid approach to uncover protein interactions involving the D2-like subfamily of dopamine receptors…