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FLNA protein, human

Known as: filamin A, alpha (actin binding protein 280), human, EC 6.3.4.4, Actin Binding Protein 280 
Filamin-A (2647 aa, ~281 kDa) is encoded by the human FLNA gene. This protein is involved in cytoskeletal remodeling.
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Filamin A (FLNa) can effect orthogonal branching of F-actin and bind many cellular constituents. FLNa dimeric subunits have N… Expand
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Highly Cited
2006
Highly Cited
2006
FilGAP is a newly recognized filamin A (FLNa)-binding RhoGTPase-activating protein. The GTPase-activating protein (GAP) activity… Expand
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Highly Cited
2006
Highly Cited
2006
Mutations in the human Filamin A (FLNA) gene disrupt neuronal migration to the cerebral cortex and cause cardiovascular defects… Expand
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Highly Cited
2006
Highly Cited
2006
Filamin A (FLNa), a dimeric actin cross-linking and scaffold protein with numerous intracellular binding partners, anchors the… Expand
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Highly Cited
2003
Highly Cited
2003
The androgen receptor (AR), a nuclear transcription factor, mediates male sexual differentiation, and its excessive action is… Expand
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Highly Cited
2002
Highly Cited
2002
Although proteins phosphorylated on tyrosine residues can be enriched by immunoprecipitation with anti-phosphotyrosine antibodies… Expand
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Highly Cited
2002
Highly Cited
2002
An absent platelet glycoprotein (GP) Ib-IX receptor results in the Bernard-Soulier syndrome and is characterized by severe… Expand
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Highly Cited
2001
Highly Cited
2001
We have used a yeast two-hybrid approach to uncover protein interactions involving the D2-like subfamily of dopamine receptors… Expand
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Highly Cited
2001
Highly Cited
2001
Filamin A (ABP‐280), which is an actin‐binding protein of 560 kDa as a dimer, can, together with actin filaments, produce an… Expand
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Highly Cited
2000
Highly Cited
2000
Proteins that bind to G protein-coupled receptors have recently been identified as regulators of receptor anchoring and signaling… Expand
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