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FLNA protein, human

Known as: filamin A, alpha (actin binding protein 280), human, EC 6.3.4.4, Actin Binding Protein 280 
Filamin-A (2647 aa, ~281 kDa) is encoded by the human FLNA gene. This protein is involved in cytoskeletal remodeling.
National Institutes of Health

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Related topics

4 relations
FLNA geneStructural gene

Broader (2)

Filamin AFilamins

Papers overview

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2018
2018
A novel truncating mutation in FLNA causes periventricular nodular heterotopia, Ehlers-Danlos-like collagenopathy and macrothrombocytopenia
2017
2017
Snail-induced epithelial to mesenchymal transition ( EMT ) and cell adhesion but its inhibition increases the migration of colon adenocarcinoma HT 29 cells
Filamin A (FLNA) is actin filament cross-linking protein involved in cancer progression. Its importance in regulating cell… 
2009
2009
FLNA, a new partner gene fused to MLL in a patient with acute myelomonoblastic leukaemia
Translocations involving chromosomal band 11q23 are found in most cases of infant acute lymphoblastic leukaemia and acute… 
2008
2008
ECSM2, An Endothelial Specific Filamin A Binding Protein That Mediates Chemotaxis
Objective—We aimed to characterize the expression and function of a novel transcript that bioinformatics analysis predicted to be… 
Review
2001
Review
2001
Molecular mechanisms of neuronal migration disorders, quo vadis?
Following terminal mitosis, neuronal precursor cells leave their site of origin and migrate towards their definitive site of… 
Highly Cited
2000
Highly Cited
2000
Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein.
Three different C-terminal regions of human endothelial actin-binding protein-280 (ABP-280 or ABP; nonmuscle filamin) were… 
1994
1994
Comparative mapping of the actin-binding protein 280 genes in human and mouse.
Two genes encode actin-binding protein 280 isoforms. ABP-280 or filamin (FLN1) is present in the cytoskeleton of many cell types… 
Highly Cited
1992
Highly Cited
1992
Localization and identification of actin structures involved in the filamin-actin interaction.
The interface between gizzard filamin and skeletal muscle actin was located on the actin monomer. Conserved sequences 105-120 and… 
1988
1988
A novel 53 kDa actin binding protein from porcine brain--further biochemical and immunological characterization.
We have previously described some of the characteristics of an actin binding protein, 53 K protein, purified from porcine brains… 
1987
1987
Calcium control of macrophage cytoplasmic gelation: evidence for the involvement of the 70,000 Mr actin-bundling protein.
Under appropriate conditions macrophage cytosolic extracts can form a three-dimensional gel network of cross-linked actin… 
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