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FLNA protein, human

Known as: filamin A, alpha (actin binding protein 280), human, EC 6.3.4.4, Actin Binding Protein 280 
Filamin-A (2647 aa, ~281 kDa) is encoded by the human FLNA gene. This protein is involved in cytoskeletal remodeling.
National Institutes of Health

Related topics

Related topics

4 relations
FLNA geneStructural gene

Broader (2)

Filamin AFilamins

Papers overview

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Highly Cited
2010
Highly Cited
2010
Differential Protein Expression Profiling by iTRAQ-Two-dimensional LC-MS/MS of Human Bladder Cancer EJ138 Cells Transfected with the Metastasis Suppressor KiSS-1 Gene*
KiSS-1 is a metastasis suppressor gene reported to be involved in the progression of several solid neoplasias. The loss of KiSS-1… 
Highly Cited
2008
Highly Cited
2008
Binding of the P2Y2 Nucleotide Receptor to Filamin A Regulates Migration of Vascular Smooth Muscle Cells
The functional expression of the G protein–coupled P2Y2 nucleotide receptor (P2Y2R) has been associated with proliferation and… 
Review
2007
Review
2007
A review of actin binding proteins: new perspectives
Actin binding proteins (ABPs) have been considered components of the cytoskeleton, which gives structure and allows mobility of… 
Highly Cited
2005
Highly Cited
2005
Ca2+ and Calmodulin Regulate the Binding of Filamin A to Actin Filaments*
Filamin A (FLNa) cross-links actin filaments (F-actin) into three-dimensional gels in cells, attaches F-actin to membrane… 
Highly Cited
2001
Highly Cited
2001
Interaction with BRCA2 Suggests a Role for Filamin-1 (hsFLNa) in DNA Damage Response*
The BRCA2 tumor suppressor plays significant roles in DNA damage response. The human actin binding protein filamin-1 (hsFLNa… 
Review
2001
Review
2001
Cell migration and cerebral cortical development
This annotation describes the clinical and pathological features of several conditions believed to result from a primary defect… 
Review
2001
Review
2001
Molecular mechanisms of neuronal migration disorders, quo vadis?
Following terminal mitosis, neuronal precursor cells leave their site of origin and migrate towards their definitive site of… 
Highly Cited
2000
Highly Cited
2000
Determination of a cAMP-dependent protein kinase phosphorylation site in the C-terminal region of human endothelial actin-binding protein.
Three different C-terminal regions of human endothelial actin-binding protein-280 (ABP-280 or ABP; nonmuscle filamin) were… 
Highly Cited
1999
Highly Cited
1999
A NOVEL HUMAN SMALL STRESS PROTEIN SELECTIVELY EXPRESSED IN CARDIOVASCULAR AND INSULIN-SENSITIVE TISSUES*
Starting with computational tools that search for tissue-selective expression of assembled expressed sequenced tags, we have… 
Highly Cited
1992
Highly Cited
1992
Localization and identification of actin structures involved in the filamin-actin interaction.
The interface between gizzard filamin and skeletal muscle actin was located on the actin monomer. Conserved sequences 105-120 and… 
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