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FLNC protein, human

Known as: FLN2 protein, human, filamin 2, ABP-L 
Filamin-C (2725 aa, ~291 kDa) is encoded by the human FLNC gene. This protein plays a role in the organization of the cytoskeleton of muscle fibers.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Individuals affected by restrictive cardiomyopathy (RCM) often develop heart failure at young ages resulting in early heart… Expand
Highly Cited
2007
Highly Cited
2007
RING-finger proteins commonly function as ubiquitin ligases that mediate protein degradation by the ubiquitin-proteasome pathway… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT FilaminC (FLNc) is the muscle-specific member of a family of actin binding proteins. Although it interacts with many… Expand
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Highly Cited
2003
Highly Cited
2003
Calpain 3 (C3) is the only muscle-specific member of the calcium-dependent protease family. Although neither its physiological… Expand
Highly Cited
2002
Highly Cited
2002
  • N. Frey, E. Olson
  • The Journal of Biological Chemistry
  • 2002
  • Corpus ID: 25072601
The Z-disc is a highly specialized multiprotein complex of striated muscles that serves as the interface of the sarcomere and the… Expand
Highly Cited
2002
Highly Cited
2002
Limb-girdle muscular dystrophy 1A (LGMD1A [MIM 159000]) is an autosomal dominant form of muscular dystrophy characterized by… Expand
Highly Cited
2001
Highly Cited
2001
To better understand the structure and function of Z lines, we used sarcomeric isoforms of alpha-actinin and gamma-filamin to… Expand
Highly Cited
2000
Highly Cited
2000
Mutations in genes encoding for the sarcoglycans, a subset of proteins within the dystrophin–glycoprotein complex, produce a limb… Expand
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Highly Cited
2000
Highly Cited
2000
We report the identification and characterization of a novel 32-kDa protein expressed in skeletal muscle and located in the Z… Expand
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Highly Cited
2000
Highly Cited
2000
Filamin, also called actin binding protein-280, is a dimeric protein that cross-links actin filaments in the cortical cytoplasm… Expand
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