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FLNC protein, human

Known as: FLN2 protein, human, filamin 2, ABP-L 
Filamin-C (2725 aa, ~291 kDa) is encoded by the human FLNC gene. This protein plays a role in the organization of the cytoskeleton of muscle fibers.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Individuals affected by restrictive cardiomyopathy (RCM) often develop heart failure at young ages resulting in early heart… Expand
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Highly Cited
2006
Highly Cited
2006
FilaminC (FLNc) is the muscle-specific member of a family of actin binding proteins. Although it interacts with many proteins… Expand
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2004
2004
We have studied a cohort of nemaline myopathy (NM) patients with mutations in the muscle alpha-skeletal actin gene (ACTA1… Expand
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2003
2003
Calpain 3 (C3) is the only muscle-specific member of the calcium-dependent protease family. Although neither its physiological… Expand
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2003
2003
N-RAP, a muscle-specific protein concentrated at myotendinous junctions in skeletal muscle and intercalated disks in cardiac… Expand
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2003
2003
Myotilin is a Z-disc protein that binds alpha-actinin, gamma-filamin and F-actin. The essential role of myotilin in skeletal… Expand
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Highly Cited
2001
Highly Cited
2001
To better understand the structure and function of Z lines, we used sarcomeric isoforms of alpha-actinin and gamma-filamin to… Expand
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2001
2001
Here we present the sequence of a 45 kb cosmid containing a previously characterized poly-morphic Mhc class II B gene (Agph-DAB1… Expand
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Highly Cited
2000
Highly Cited
2000
Mutations in genes encoding for the sarcoglycans, a subset of proteins within the dystrophin–glycoprotein complex, produce a limb… Expand
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Highly Cited
2000
Highly Cited
2000
We report the identification and characterization of a novel 32-kDa protein expressed in skeletal muscle and located in the Z… Expand
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