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Fibroblast Growth Factor Receptor 2

Known as: BEK Fibroblast Growth Factor Receptor, BEK Fibroblast Growth Factor Receptor Kinase, fgfr2 
A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor… 
National Institutes of Health

Related topics

Related topics

17 relations
AcrocephalosyndactyliaAntley-Bixler Syndrome PhenotypeCraniofacial DysostosisFGFR2 gene

Narrower (6)

FGFR2 protein, humanFibroblast Growth Factor Receptor 2 Isoform IIIbFibroblast Growth Factor Receptor 2bFibroblast Growth Factor Receptor 2c

Broader (1)

Fibroblast Growth Factor Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
Fibroblast growth factor receptor 2 (FGFR2) is a membrane-spanning tyrosine kinase that mediates signaling for FGFs. Recent… 
Highly Cited
2015
Highly Cited
2015
Expression profiles of HER2, EGFR, MET and FGFR2 in a large cohort of patients with gastric adenocarcinoma
BackgroundSome tyrosine kinase receptors (RTKs) play critical roles in gastric cancer progression. Not only trastuzumab, but also… 
Highly Cited
2008
Highly Cited
2008
Influence of hydrogel mechanical properties and mesh size on vocal fold fibroblast extracellular matrix production and phenotype.
Highly Cited
2007
Highly Cited
2007
Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis
The fibroblast growth factor (FGF) family consists of 22 members and regulates a broad spectrum of biological activities by… 
Highly Cited
2000
Highly Cited
2000
Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome.
Craniosynostosis syndromes are autosomal dominant human skeletal diseases that result from various mutations in fibroblast growth… 
Highly Cited
1999
Highly Cited
1999
Fgfr2 is required for limb outgrowth and lung-branching morphogenesis.
The aim of this study was to clarify the role of Fgfr2 during later stages of embryonic development. Of two previously reported… 
Highly Cited
1996
Highly Cited
1996
Expression and Biological Activity of Mouse Fibroblast Growth Factor-9 (*)
Receptor specificity is an essential mechanism governing the activity of fibroblast growth factors (FGF). To begin to understand… 
Review
1995
Review
1995
Analysis of phenotypic features and FGFR2 mutations in Apert syndrome.
A phenotypic and genotypic survey was conducted on 36 Apert syndrome patients. In all but one patient, an FGFR2 mutation, either… 
Highly Cited
1992
Highly Cited
1992
A confined variable region confers ligand specificity on fibroblast growth factor receptors: implications for the origin of the immunoglobulin fold.
Binding of cellular growth factors to their receptors constitutes a highly specific interaction and the basis for cell and tissue… 
Highly Cited
1991
Highly Cited
1991
Multiple mRNAs code for proteins related to the BEK fibroblast growth factor receptor.
The BEK transmembrane protein tyrosine kinase is a receptor for both acidic and basic fibroblast growth factors. We identify… 
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