Fibroblast Growth Factor Receptor 2

Known as: BEK Fibroblast Growth Factor Receptor, BEK Fibroblast Growth Factor Receptor Kinase, fgfr2 
A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor… (More)
National Institutes of Health

Related topics

Related topics

17 relations
AcrocephalosyndactyliaAntley-Bixler Syndrome PhenotypeCraniofacial DysostosisFGFR2 gene
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Narrower (6)

FGFR2 protein, humanFibroblast Growth Factor Receptor 2 Isoform IIIbFibroblast Growth Factor Receptor 2bFibroblast Growth Factor Receptor 2c
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Broader (1)

Fibroblast Growth Factor Receptors

Papers overview

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Review
2017
Review
2017
Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
Fibroblast growth factor receptor 2 (FGFR2) is a membrane-spanning tyrosine kinase that mediates signaling for FGFs. Recent… (More)
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2008
2008
Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis.
The fibroblast growth factor (FGF) regulates a broad spectrum of biological activities by activation of transmembrane FGF… (More)
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2007
2007
Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis.
The fibroblast growth factor (FGF) family consists of 22 members and regulates a broad spectrum of biological activities by… (More)
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2005
2005
Evaluation of the fibroblast growth factor system as a potential target for therapy in human prostate cancer
Overexpression of fibroblast growth factors (FGFs) has been implicated in prostate carcinogenesis. FGFs function via their high… (More)
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Highly Cited
2003
Highly Cited
2003
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth.
Human craniosynostosis syndromes, resulting from activating or neomorphic mutations in fibroblast growth factor receptor 2 (FGFR2… (More)
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Highly Cited
2002
Highly Cited
2002
Genomic screening of fibroblast growth-factor receptor 2 reveals a wide spectrum of mutations in patients with syndromic craniosynostosis.
It has been known for several years that heterozygous mutations of three members of the fibroblast growth-factor-receptor family… (More)
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2001
2001
Uncoupling fibroblast growth factor receptor 2 ligand binding specificity leads to Apert syndrome-like phenotypes.
D missense mutations in the genes encoding fibroblast growth factor receptors (FGFRs) 1–3 are the etiology of many… (More)
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Highly Cited
2000
Highly Cited
2000
Gene expression patterns of the fibroblast growth factors and their receptors during myogenesis of rat satellite cells.
Satellite cells are the myogenic precursors in postnatal muscle and are situated beneath the myofiber basement membrane. We… (More)
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Highly Cited
1999
Highly Cited
1999
Skeletal muscle satellite cell proliferation in response to members of the fibroblast growth factor family and hepatocyte growth factor.
Fibroblast growth factors (FGF) have the ability to regulate satellite cell proliferation in culture and in muscle tissue, but… (More)
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Highly Cited
1992
Highly Cited
1992
Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues.
The expression of basic fibroblast growth factor (bFGF) and two of its receptors, FGFR1 and FGFR2, was detected using the… (More)
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