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Fibroblast Growth Factor Receptor 2 Isoform IIIb

Known as: FGFR-2 IIIb, FGFR2IIIb, FGFR2 IIIb 
An isoform of fibroblast growth factor receptor 2 where alternative splicing leads to the expression of the IIIb exon encoding the second half of the… 
National Institutes of Health

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Related topics

27 relations
Cell Differentiation processCell ProliferationCell Proliferation Regulatory ProcessEnzyme Gene
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Fibroblast Growth Factor Receptor 2

Papers overview

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Highly Cited
2009
Highly Cited
2009
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.
Cell-type-specific expression of epithelial and mesenchymal isoforms of Fibroblast Growth Factor Receptor 2 (FGFR2) is achieved… 
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Highly Cited
2008
Highly Cited
2008
Involvement of Fibroblast Growth Factor Receptor 2 Isoform Switching in Mammary Oncogenesis
We identified the IIIb C2 epithelial cell–specific splice variant of fibroblast growth factor receptor 2 (FGFR2 IIIb C2) receptor… 
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Review
2004
Review
2004
Epithelial Cell Plasticity in Development and Tumor Progression
Various mechanisms of epithelial cell plasticity in morphogenesis have been studied at the genetic and molecular levels. Several… 
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Highly Cited
2003
Highly Cited
2003
A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning
To understand the role Fgf signalling in skin and hair follicle development, we analysed the phenotype of mice deficient for… 
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Highly Cited
2002
Highly Cited
2002
The IIIc alternative of Fgfr2 is a positive regulator of bone formation.
Fibroblast growth factor receptor type 2 (FGFR2) plays major roles in development. Like FGFR1 and FGFR3, it exists as two splice… 
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Highly Cited
2002
Highly Cited
2002
Regulation of thymic epithelium by keratinocyte growth factor.
Here we demonstrate that keratinocyte growth factor (KGF) and FGFR2IIIb signaling can affect development and function of thymic… 
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Highly Cited
2002
Highly Cited
2002
Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation
Pancreatic development is a classic example of epithelium–mesenchyme interaction. During embryonic life, signals from the… 
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Highly Cited
2001
Highly Cited
2001
Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4.
Mice deficient for FgfR2-IIIb were generated by placing translational stop codons and an IRES-LacZ cassette into exon IIIb of… 
Highly Cited
1999
Highly Cited
1999
Tumour suppressive properties of fibroblast growth factor receptor 2-IIIb in human bladder cancer
FGFRs (fibroblast growth factor receptors) are encoded by four genes (FGFR1 – 4). Alternative splicing results in various… 
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Highly Cited
1997
Highly Cited
1997
Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells.
Progressive loss of the differentiated phenotype and communication with stroma accompanies the transition of nonmalignant rat… 
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