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Fibroblast Growth Factor Receptor 2 Isoform IIIb
Known as:
FGFR-2 IIIb
, FGFR2IIIb
, FGFR2 IIIb
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An isoform of fibroblast growth factor receptor 2 where alternative splicing leads to the expression of the IIIb exon encoding the second half of the…
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National Institutes of Health
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Related topics
Related topics
27 relations
Cell Differentiation process
Cell Proliferation
Cell Proliferation Regulatory Process
Enzyme Gene
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Broader (1)
Fibroblast Growth Factor Receptor 2
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.
Claude C. Warzecha
,
Trey K. Sato
,
B. Nabet
,
J. Hogenesch
,
R. Carstens
Molecules and Cells
2009
Corpus ID: 18916526
Highly Cited
2008
Highly Cited
2008
Involvement of Fibroblast Growth Factor Receptor 2 Isoform Switching in Mammary Oncogenesis
J. Cha
,
Q. Lambert
,
G. Reuther
,
C. Der
Molecular Cancer Research
2008
Corpus ID: 30235442
We identified the IIIb C2 epithelial cell–specific splice variant of fibroblast growth factor receptor 2 (FGFR2 IIIb C2) receptor…
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Highly Cited
2007
Highly Cited
2007
Selective over‐expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer
K. Sahadevan
,
S. Darby
,
H. Leung
,
M. Mathers
,
C. Robson
,
V. Gnanapragasam
Journal of Pathology
2007
Corpus ID: 28713096
Fibroblast growth factor receptors (FGFRs) mediate the tumourigenic effects of FGFs in prostate cancer. These receptors are…
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Review
2004
Review
2004
Epithelial Cell Plasticity in Development and Tumor Progression
J. Thiery
,
D. Chopin
Cancer Metastasis Review
2004
Corpus ID: 22020587
Various mechanisms of epithelial cell plasticity in morphogenesis have been studied at the genetic and molecular levels. Several…
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Highly Cited
2003
Highly Cited
2003
A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning
A. Petiot
,
F. Conti
,
R. Grose
,
J. Revest
,
K. Hodivala-Dilke
,
C. Dickson
Development
2003
Corpus ID: 42407216
To understand the role Fgf signalling in skin and hair follicle development, we analysed the phenotype of mice deficient for…
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Highly Cited
2002
Highly Cited
2002
The IIIc alternative of Fgfr2 is a positive regulator of bone formation.
V. P. Eswarakumar
,
E. Monsonego-Ornan
,
M. Pines
,
I. Antonopoulou
,
G. Morriss-Kay
,
P. Lonai
Development
2002
Corpus ID: 11830426
Fibroblast growth factor receptor type 2 (FGFR2) plays major roles in development. Like FGFR1 and FGFR3, it exists as two splice…
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Highly Cited
2002
Highly Cited
2002
Regulation of thymic epithelium by keratinocyte growth factor.
M. Erickson
,
S. Morkowski
,
+6 authors
A. Farr
Blood
2002
Corpus ID: 13005996
Here we demonstrate that keratinocyte growth factor (KGF) and FGFR2IIIb signaling can affect development and function of thymic…
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Highly Cited
2001
Highly Cited
2001
Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4.
J. Revest
,
B. Spencer‐Dene
,
K. Kerr
,
L. De Moerlooze
,
I. Rosewell
,
C. Dickson
Developmental Biology
2001
Corpus ID: 26419601
Mice deficient for FgfR2-IIIb were generated by placing translational stop codons and an IRES-LacZ cassette into exon IIIb of…
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Highly Cited
1999
Highly Cited
1999
Tumour suppressive properties of fibroblast growth factor receptor 2-IIIb in human bladder cancer
D. Ricol
,
D. Cappellen
,
+9 authors
F. Radvanyi
Oncogene
1999
Corpus ID: 23933445
FGFRs (fibroblast growth factor receptors) are encoded by four genes (FGFR1 – 4). Alternative splicing results in various…
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Highly Cited
1997
Highly Cited
1997
Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells.
S. Feng
,
F. Wang
,
A. Matsubara
,
M. Kan
,
W. Mckeehan
Cancer Research
1997
Corpus ID: 45548650
Progressive loss of the differentiated phenotype and communication with stroma accompanies the transition of nonmalignant rat…
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