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FGFR2 gene

Known as: FIBROBLAST GROWTH FACTOR RECEPTOR BEK, FGFR2, CEK3 
This gene plays a role in mitogenesis and differentiation and mutations in the gene are associated with craniosynostotic syndromes and bone… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
We sought to identify fibroblast growth factor receptor 2 (FGFR2) kinase domain mutations that confer resistance to the pan-FGFR… Expand
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Highly Cited
2013
Highly Cited
2013
The fibroblast growth factor receptor 2 (FGFR2) locus has been consistently identified as a breast cancer risk locus in… Expand
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Highly Cited
2008
Highly Cited
2008
Oncogenic activation of tyrosine kinases is a common mechanism of carcinogenesis and, given the druggable nature of these enzymes… Expand
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Highly Cited
2005
Highly Cited
2005
Activating mutations in fibroblast growth factor receptor 2 (FGFR2) cause several craniosynostosis syndromes by affecting the… Expand
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Highly Cited
2003
Highly Cited
2003
Observed mutation rates in humans appear higher in male than female gametes and often increase with paternal age. This bias… Expand
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Highly Cited
2003
Highly Cited
2003
Human craniosynostosis syndromes, resulting from activating or neomorphic mutations in fibroblast growth factor receptor 2 (FGFR2… Expand
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Highly Cited
2000
Highly Cited
2000
The fibroblast growth factor receptor 2 gene is differentially spliced to encode two transmembrane tyrosine kinase receptor… Expand
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Highly Cited
1995
Highly Cited
1995
Apert syndrome is a distinctive human malformation comprising craniosynostosis and severe syndactyly of the hands and feet. We… Expand
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Highly Cited
1995
Highly Cited
1995
Mutations in the fibroblast growth factor receptor 2 (FGFR2) gene have been identified in Crouzon syndrome, an autosomal dominant… Expand
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Highly Cited
1994
Highly Cited
1994
Crouzon syndrome is an autosomal dominant condition causing premature fusion of the cranial sutures (craniosynostosis) and maps… Expand
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