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FGFR2 gene

Known as: FIBROBLAST GROWTH FACTOR RECEPTOR BEK, FGFR2, CEK3 
This gene plays a role in mitogenesis and differentiation and mutations in the gene are associated with craniosynostotic syndromes and bone… 
National Institutes of Health

Related topics

Related topics

19 relations
AcrocephalosyndactyliaCell Differentiation processCell Proliferation Regulatory ProcessEpithelial Cell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Therapeutic Effect of Nanogel-Based Delivery of Soluble FGFR2 with S252W Mutation on Craniosynostosis
Apert syndrome is an autosomal dominantly inherited disorder caused by missense mutations in fibroblast growth factor receptor 2… 
Review
2012
Review
2012
The Fgfr2W290R mouse model of Crouzon syndrome
PurposeThis study aimed to review and discuss the utility of the Fgfr2W290R mouse mutant as a model of human Crouzon syndrome… 
2012
2012
Evaluation of breast cancer susceptibility loci on 2q35, 3p24, 17q23 and FGFR2 genes in Taiwanese women with breast cancer.
AIM Breast cancer is the most common cancer in women. In recent years, mounting evidence has identified the possibility that 2q35… 
2009
2009
Utilization of Lactobacillus fermentum and Saccharomyces cerevisiae as starter cultures in the production of 'dolo'.
Objective: The present study was carried out to evaluate the potential of representative strains of predominant lactic acid… 
2008
2008
Identification of an Intronic Splicing Enhancer Essential for the Inclusion of FGFR2 Exon IIIc*
The ligand specificity of fibroblast growth factor receptor 2 (FGFR2) is determined by the alternative splicing of exons 8 (IIIb… 
Highly Cited
2002
Highly Cited
2002
A Non-sequence-specific Double-stranded RNA Structural Element Regulates Splicing of Two Mutually Exclusive Exons of Fibroblast Growth Factor Receptor 2 (FGFR2)*
Alternative splicing of fibroblast growth factor receptor 2 (FGFR2) mutually exclusive exons IIIb and IIIc represents a tightly… 
Highly Cited
2001
Highly Cited
2001
Role of N‐Cadherin and Protein Kinase C in Osteoblast Gene Activation Induced by the S252W Fibroblast Growth Factor Receptor 2 Mutation in Apert Craniosynostosis
Apert (Ap) syndrome is characterized by premature cranial suture ossification caused by fibroblast growth factor receptor 2 (FGFR… 
1998
1998
The mutations in FGFR2-associated craniosynostoses are clustered in five structural elements of immunoglobulin-like domain III of the receptor
Abstract Exons 5 and 7 of the fibroblast growth factor receptor 2 (FGFR2) gene code for immunoglobulin-like domain III (IgIII… 
1997
1997
A novel mutation (a886g) in exon 5 of FGFR2 in members of a family with Crouzon phenotype and plagiocephaly.
We identified a novel mutation in members of a family with signs of Crouzon syndrome and plagiocephaly. In affected members of… 
Highly Cited
1996
Highly Cited
1996
FGFR2 exon IIIa and IIIc mutations in Crouzon, Jackson-Weiss, and Pfeiffer syndromes: evidence for missense changes, insertions, and a deletion due to alternative RNA splicing.
Fibroblast growth factor receptor 2 (FGFR2) mutations have been associated with the craniosynostotic conditions Crouzon, Jackson… 
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