FGFR2 gene

Known as: FIBROBLAST GROWTH FACTOR RECEPTOR BEK, FGFR2, CEK3 
This gene plays a role in mitogenesis and differentiation and mutations in the gene are associated with craniosynostotic syndromes and bone… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
0102019902018

Papers overview

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Highly Cited
2008
Highly Cited
2008
Oncogenic activation of tyrosine kinases is a common mechanism of carcinogenesis and, given the druggable nature of these enzymes… (More)
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Highly Cited
2005
Highly Cited
2005
Activating mutations in fibroblast growth factor receptor 2 (FGFR2) cause several craniosynostosis syndromes by affecting the… (More)
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Highly Cited
2003
Highly Cited
2003
Human craniosynostosis syndromes, resulting from activating or neomorphic mutations in fibroblast growth factor receptor 2 (FGFR2… (More)
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Highly Cited
2000
Highly Cited
2000
The fibroblast growth factor receptor 2 gene is differentially spliced to encode two transmembrane tyrosine kinase receptor… (More)
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2000
2000
Crouzon syndrome and Pfeiffer syndrome are both autosomal dominant craniosynostotic disorders that can be caused by mutations in… (More)
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1998
1998
Multiple human skeletal and craniosynostosis disorders, including Crouzon, Pfeiffer, Jackson-Weiss, and Apert syndromes, result… (More)
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Highly Cited
1996
Highly Cited
1996
Apert syndrome results from one or other of two specific nucleotide substitutions, both C→G transversions, in the fibroblast… (More)
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Highly Cited
1996
Highly Cited
1996
Fibroblast growth factor receptor 2 (FGFR2) mutations have been associated with the craniosynostotic conditions Crouzon, Jackson… (More)
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Highly Cited
1995
Highly Cited
1995
Mutations in the fibroblast growth factor receptor 2 (FGFR2) gene have been identified in Crouzon syndrome, an autosomal dominant… (More)
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Highly Cited
1994
Highly Cited
1994
Crouzon syndrome is an autosomal dominant condition causing premature fusion of the cranial sutures (craniosynostosis) and maps… (More)
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