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Fibroblast Growth Factor Receptors

Known as: FGF-R, Fibroblast Growth Factor Receptor Family, FGFR 
Specific molecular sites or structures on cell membranes that react with FIBROBLAST GROWTH FACTORS (both the basic and acidic forms), their analogs… 
National Institutes of Health

Related topics

Related topics

34 relations
Cell Differentiation processCell ProliferationCell Proliferation Regulatory ProcessEnzyme Gene

Narrower (5)

FOP-FGFR1 fusion protein, humanFibroblast Growth Factor Receptor 2fibroblast growth factor receptor, Halocynthia roretzifibroblast growth factor-21 receptor, mouse

Papers overview

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Highly Cited
2017
Highly Cited
2017
Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of…
Purpose This two-part, first-in-human study was initiated in patients with advanced solid tumors harboring genetic alterations in… 
Highly Cited
2012
Highly Cited
2012
AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family.
The fibroblast growth factor (FGF) signaling axis is increasingly implicated in tumorigenesis and chemoresistance. Several small… 
Review
2010
Review
2010
Roles of Fibroblast Growth Factor Receptors in Carcinogenesis
The fibroblast growth factor receptors (FGFR) play essential roles both during development and in the adult. Upon ligand binding… 
Review
2009
Review
2009
The role of fibroblast growth factors in tumor growth.
Biological processes that drive cell growth are exciting targets for cancer therapy. The fibroblast growth factor (FGF) signaling… 
Review
2004
Review
2004
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
In addition to their adhesive functions, cell-adhesion molecules modulate signal-transduction pathways by interacting with… 
Highly Cited
2000
Highly Cited
2000
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
Fibroblast growth factors (FGFs) are a large family of structurally related proteins with a wide range of physiological and… 
Highly Cited
2000
Highly Cited
2000
Signaling by Fibroblast Growth Factors (Fgf) and Fibroblast Growth Factor Receptor 2 (Fgfr2)–Activating Mutations Blocks Mineralization and Induces Apoptosis in Osteoblasts
Fibroblast growth factors (FGF) play a critical role in bone growth and development affecting both chondrogenesis and… 
Review
1999
Review
1999
Signal transduction by fibroblast growth factor receptors.
The fibroblast growth factor family, with its prototype members acidic FGF (FGF-1) and basic FGF (FGF-2), binds to four related… 
Highly Cited
1994
Highly Cited
1994
A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome
Pfeiffer syndrome (PS) is one of the classic autosomal dominant craniosynostosis syndromes with craniofacial anomalies and… 
Highly Cited
1993
Highly Cited
1993
Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2).
The gene for fibroblast growth factor receptor-2 (FGFR2) encodes two splice variants designated here as keratinocyte growth… 
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