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Fibroblast Growth Factor Receptors
Known as:
FGF-R
, Fibroblast Growth Factor Receptor Family
, FGFR
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Specific molecular sites or structures on cell membranes that react with FIBROBLAST GROWTH FACTORS (both the basic and acidic forms), their analogs…
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National Institutes of Health
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Related topics
Related topics
34 relations
Cell Differentiation process
Cell Proliferation
Cell Proliferation Regulatory Process
Enzyme Gene
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Narrower (5)
FOP-FGFR1 fusion protein, human
Fibroblast Growth Factor Receptor 2
fibroblast growth factor receptor, Halocynthia roretzi
fibroblast growth factor-21 receptor, mouse
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21*
H. Kurosu
,
Mihwa Choi
,
+7 authors
M. Kuro-o
Journal of Biological Chemistry
2007
Corpus ID: 29091092
The fibroblast growth factor (FGF) 19 subfamily of ligands, FGF19, FGF21, and FGF23, function as hormones that regulate bile acid…
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Highly Cited
2006
Highly Cited
2006
Regulation of Fibroblast Growth Factor-23 Signaling by Klotho*
H. Kurosu
,
Y. Ogawa
,
+8 authors
M. Kuro-o
Journal of Biological Chemistry
2006
Corpus ID: 20697776
The aging suppressor gene Klotho encodes a single-pass transmembrane protein. Klotho-deficient mice exhibit a variety of aging…
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Review
2005
Review
2005
Cellular signaling by fibroblast growth factor receptors.
V. P. Eswarakumar
,
I. Lax
,
J. Schlessinger
Cytokine & growth factor reviews
2005
Corpus ID: 7717479
Review
2005
Review
2005
Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis.
M. Presta
,
P. Dell’Era
,
S. Mitola
,
E. Moroni
,
R. Ronca
,
M. Rusnati
Cytokine & growth factor reviews
2005
Corpus ID: 45224703
Highly Cited
2000
Highly Cited
2000
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.
L. Moerlooze
,
B. Spencer‐Dene
,
J. Revest
,
M. Hajihosseini
,
I. Rosewell
,
C. Dickson
Development
2000
Corpus ID: 15091824
The fibroblast growth factor receptor 2 gene is differentially spliced to encode two transmembrane tyrosine kinase receptor…
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Highly Cited
2000
Highly Cited
2000
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
L. Pellegrini
,
D. Burke
,
F. Delft
,
B. Mulloy
,
T. Blundell
Nature
2000
Corpus ID: 4418272
Fibroblast growth factors (FGFs) are a large family of structurally related proteins with a wide range of physiological and…
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Review
1999
Review
1999
Signal transduction by fibroblast growth factor receptors.
P. Klint
,
L. Claesson-Welsh
Frontiers in Bioscience
1999
Corpus ID: 11068413
The fibroblast growth factor family, with its prototype members acidic FGF (FGF-1) and basic FGF (FGF-2), binds to four related…
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Highly Cited
1997
Highly Cited
1997
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.
M. Mohammadi
,
G. Mcmahon
,
+5 authors
J. Schlessinger
Science
1997
Corpus ID: 26856676
A new class of protein tyrosine kinase inhibitors was identified that is based on an oxindole core (indolinones). Two compounds…
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Highly Cited
1994
Highly Cited
1994
Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia
F. Rousseau
,
J. Bonaventure
,
+5 authors
A. Munnich
Nature
1994
Corpus ID: 4303242
ACHONDROPLASIA, the most common cause of chondrodysplasia in man (1 in 15,000 live births), is a condition of unknown origin…
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Highly Cited
1994
Highly Cited
1994
A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome
M. Muenke
,
U. Schell
,
+8 authors
R. Winter
Nature Genetics
1994
Corpus ID: 40033932
Pfeiffer syndrome (PS) is one of the classic autosomal dominant craniosynostosis syndromes with craniofacial anomalies and…
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