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Fc-Gamma Receptor II

Known as: CD32, Fc Fragment of IgG, Low Affinity II, Receptor for, Fc Fragment of IgG, Low Affinity II, Receptor (CD32) 
A family of low affinity receptors for aggregates of gamma immunoglobulins (IgG). These receptors are expressed on the surface of monocytes… 
National Institutes of Health

Related topics

Related topics

21 relations
Antimicrobial EffectCD32 AntigensCell-Mediated CytolysisClusters of differentiation

Narrower (3)

FCGR2A protein, humanFCGR2B protein, humanFc gamma receptor IIA

Papers overview

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Highly Cited
1995
Highly Cited
1995
Multiple Regions of Human FcγRII (CD32) Contribute to the Binding of IgG (*)
The low affinity receptor for IgG, FcγRII (CD32), has a wide distribution on hematopoietic cells where it is responsible for a… 
Highly Cited
1994
Highly Cited
1994
Identification of the IgG binding site of the human low affinity receptor for IgG Fc gamma RII. Enhancement and ablation of binding by site-directed mutagenesis.
Fc receptor-antibody interactions are key mechanisms through which antibody effector functions are mediated. The low affinity… 
Highly Cited
1992
Highly Cited
1992
Antibodies against synthetic peptides used to determine the topology and site of glycosylation of the cGMP-gated channel from bovine rod photoreceptors.
Highly Cited
1992
Highly Cited
1992
Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression.
Certain monoclonal antibodies (MoAbs) specific for platelet membrane glycoproteins are known to be capable of activating… 
Highly Cited
1990
Highly Cited
1990
Characterization of murine lung dendritic cells: similarities to Langerhans cells and thymic dendritic cells
Dendritic cells (DC) are potent accessory cells (AC) for the initiation of primary immune responses. Although murine lymphoid DC… 
Highly Cited
1990
Highly Cited
1990
Human epidermal Langerhans cells express only the 40-kilodalton Fc gamma receptor (FcRII).
In man, three distinct classes of receptors for the Fc fragments of IgG (FcRI, II, III) have been defined. The FcRI has a Mr of… 
Highly Cited
1990
Highly Cited
1990
The monoclonal antibody 41H16 detects the Leu 4 responder form of human Fc gamma RII.
Human FcR for IgG can be divided into three classes (Fc gamma RI, II, and III) based on their structure and reactivity with mAb… 
Highly Cited
1990
Highly Cited
1990
Signal transduction by the platelet Fc receptor.
We have evaluated the mechanism by which crosslinking human platelet Fc receptor (FcR) for IgG triggers platelet aggregation and… 
Highly Cited
1989
Highly Cited
1989
The FCγ receptor of natural killer cells is a phospholipid-linked membrane protein
THIS letter reported the isolation and partial characterization of a cDNA clone encoding a phospholipid-anchored form of CD16… 
Highly Cited
1985
Highly Cited
1985
Two distinct classes of IgG Fc receptors on a human monocyte line (U937) defined by differences in binding of murine IgG subclasses at low ionic strength.
We have defined two distinct classes of IgG Fc receptors (FcR) on cells of a human monocytic line (U937) by analyzing the direct… 
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