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Fanconi Anemia Complementation Group D2 Protein

Known as: Fanconi Anemia Complementation Group D2 Protein [Chemical/Ingredient], FANCD2, Fanconi Anemia Group D2 Complementing Protein 
A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to… Expand
National Institutes of Health

Related topics

Related topics

15 relations
BARD1 PathwayCell Cycle ControlDNA RepairDNA Repair Gene
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Papers overview

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Highly Cited
2010
Highly Cited
2010
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
The Fanconi anemia (FA) pathway is responsible for interstrand crosslink repair. At the heart of this pathway is the FANCI-FAND2… Expand
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Highly Cited
2009
Highly Cited
2009
The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair
Fanconi Cross-Links Fanconi anemia is a rare genetic disease characterized by bone marrow failure, developmental abnormalities… Expand
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Highly Cited
2009
Highly Cited
2009
Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.
Fanconi anemia (FA) is a human genetic disease characterized by chromosome instability, cancer predisposition, and cellular… Expand
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Highly Cited
2007
Highly Cited
2007
Proteasome function is required for DNA damage response and fanconi anemia pathway activation.
Proteasome inhibitors sensitize tumor cells to DNA-damaging agents, including ionizing radiation (IR), and DNA cross-linking… Expand
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Highly Cited
2005
Highly Cited
2005
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
Fanconi anemia is a genetic disease characterized by genomic instability and cancer predisposition. Nine genes involved in… Expand
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Review
2003
Review
2003
The Fanconi anaemia/BRCA pathway
Fanconi anaemia (FA) is a rare genetic cancer-susceptibility syndrome that is characterized by congenital abnormalities, bone… Expand
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Highly Cited
2003
Highly Cited
2003
A novel ubiquitin ligase is deficient in Fanconi anemia
Fanconi anemia is a recessively inherited disease characterized by congenital defects, bone marrow failure and cancer… Expand
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Highly Cited
2002
Highly Cited
2002
Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways
Fanconi anemia (FA) and ataxia telangiectasia (AT) are clinically distinct autosomal recessive disorders characterized by… Expand
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Highly Cited
2002
Highly Cited
2002
S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51.
Fanconi anemia (FA) is a human autosomal recessive cancer susceptibility disorder characterized by cellular sensitivity to… Expand
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Highly Cited
2001
Highly Cited
2001
Positional cloning of a novel Fanconi anemia gene, FANCD2.
Fanconi anemia (FA) is a genetic disease with birth defects, bone marrow failure, and cancer susceptibility. To date, genes for… Expand
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