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Fanconi Anemia Complementation Group D2 Protein

Known as: Fanconi Anemia Complementation Group D2 Protein [Chemical/Ingredient], FANCD2, Fanconi Anemia Group D2 Complementing Protein 
A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
0102020012017

Related topics

Related topics

14 relations
Cell Cycle ControlDNA RepairDNA Repair GeneFANCD2 gene
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Fanconi Anemia Complementation Group D2 Protein
physiological aspects
DNA Repair
In Blood
Cell Cycle Control
chemical synthesis

Papers overview

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Highly Cited
2009
Highly Cited
2009
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
Several inherited syndromes in humans are associated with cancer predisposition. The gene products defective in two of these… (More)
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Highly Cited
2007
Highly Cited
2007
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway
Activation of the Fanconi anemia (FA) DNA damage–response pathway results in the monoubiquitination of FANCD2, which is regulated… (More)
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Highly Cited
2007
Highly Cited
2007
Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair
Fanconi anemia (FA) is a developmental and cancer-predisposition syndrome caused by mutations in genes controlling DNA… (More)
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Highly Cited
2005
Highly Cited
2005
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M
Fanconi anemia is a genetic disease characterized by genomic instability and cancer predisposition. Nine genes involved in… (More)
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Highly Cited
2005
Highly Cited
2005
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
Protein ubiquitination and deubiquitination are dynamic processes implicated in the regulation of numerous cellular pathways… (More)
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Highly Cited
2003
Highly Cited
2003
A novel ubiquitin ligase is deficient in Fanconi anemia
Fanconi anemia is a recessively inherited disease characterized by congenital defects, bone marrow failure and cancer… (More)
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Highly Cited
2003
Highly Cited
2003
Disruption of the Fanconi anemia–BRCA pathway in cisplatin-sensitive ovarian tumors
Ovarian tumor cells are often genomically unstable and hypersensitive to cisplatin. To understand the molecular basis for this… (More)
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Highly Cited
2002
Highly Cited
2002
S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51.
Fanconi anemia (FA) is a human autosomal recessive cancer susceptibility disorder characterized by cellular sensitivity to… (More)
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Highly Cited
2002
Highly Cited
2002
Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways
Fanconi anemia (FA) and ataxia telangiectasia (AT) are clinically distinct autosomal recessive disorders characterized by… (More)
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Highly Cited
2001
Highly Cited
2001
Positional cloning of a novel Fanconi anemia gene, FANCD2.
Fanconi anemia (FA) is a genetic disease with birth defects, bone marrow failure, and cancer susceptibility. To date, genes for… (More)
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