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FZD8 gene

Known as: frizzled class receptor 8, FRIZZLED, DROSOPHILA, HOMOLOG OF, 8, Frizzled Class Receptor 8 Gene 
This gene plays a role in cell signaling.
National Institutes of Health

Related topics

Related topics

6 relations
FZD10 geneFzd8 protein, humanG Protein-Coupled Receptor SignalingLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Role of WNT5A receptors FZD5 and RYK in prostate cancer cells
Prostate cancer is the most common malignancy in men and has a high propensity to metastasize to bone. WNT5A has recently been… 
2018
2018
Dysregulated genes targeted by microRNAs and metabolic pathways in bladder cancer revealed by bioinformatics methods
The present study aimed to identify bladder cancer-associated microRNAs (miRNAs) and target genes, and further analyze the… 
2014
2014
Novel homozygous mutations in the WNT10B gene underlying autosomal recessive split hand/foot malformation in three consanguineous families.
2014
2014
Abstract 1907: Wnt pathway antagonist OMP-54F28 (FZD8-Fc) inhibits tumor growth and reduces tumor-initiating cell frequency in patient-derived hepatocellular carcinoma and ovarian cancer xenograft…
The Wnt/beta-catenin pathway, which signals through the Frizzled (FZD) receptor family and several co-receptors, has long been… 
2011
2011
Expression profile of frizzled receptors in human medulloblastomas
Secreted WNT proteins signal through ten receptors of the frizzled (FZD) family. Because of the relevance of the WNT/β-catenin… 
2005
2005
Comparative genomics on Wnt8a and Wnt8b genes.
WNT family ligands transduce signals through FZD1, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9, FZD10, LRP5, LRP6, ROR1, ROR2… 
2005
2005
Comparative genomics on ROR1 and ROR2 orthologs.
Transmembrane proteins with extracellular Frizzled domain, such as ROR1, ROR2, MUSK, MFRP, FZD1, FZD2, FZD3, FZD4, FZD5, FZD6… 
2005
2005
Identification and characterization of rat Ankrd6 gene in silico.
WNT signals are transduced to the beta-catenin pathway or the planar cell polarity (PCP) pathway. Drosophila Frizzled (Fz… 
Highly Cited
2001
Highly Cited
2001
Expression profiles of 10 members of Frizzled gene family in human gastric cancer.
Frizzled (FZD) genes encode seven-transmembrane type WNT receptors, which are implicated in carcinogenesis and embryogenesis. We… 
2001
2001
Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2.
Mouse Frizzled-8, encoding a WNT receptor, is a potent cancer-associated gene to activate the beta-catenin-TCF pathway. However… 
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