FYVE, RhoGEF and PH Domain-Containing Protein 4
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Background: Charcot Marie Tooth (CMT) disease is a heterogeneous group of inherited peripheral motor and sensory neuropathies… Expand • Introduction • Molecular structures of frabin and other related GEFs • Tissue distribution, subcellular localization and… Expand Charcot-Marie-Tooth (CMT) disorders are a clinically and genetically heterogeneous group of hereditary motor and sensory… Expand Cryptosporidium parvum invades target epithelia via a mechanism that involves host cell actin reorganization. We previously… Expand Mutations in faciogenital dysplasia protein (Fgd1) result in the human disease faciogenital dysplasia (FGDY). Fgd1 contains a… Expand Background: Invadopodia are membrane protrusions into the extracellular matrix by aggressive tumour cells. These structures are… Expand Background: Frabin is an actin filament (F‐actin)‐binding protein with GDP/GTP exchange activity specific for Cdc42 small G… Expand Frabin is an actin filament-binding protein which shows GDP/GTP exchange activity specific for Cdc42 small G protein and induces… Expand We have recently isolated a novel actin filament-binding protein, named frabin. Frabin has one actin filament-binding domain (ABD… Expand We purified from rat brain a novel F-actin-binding protein with a M r of about 105,000 (p105), which was estimated by SDS… Expand