FYVE, RhoGEF and PH Domain-Containing Protein 4

Known as: FGD1-Related F-Actin-Binding Protein, Actin Filament-Binding Protein Frabin, Actin-Filament Binding Protein Frabin 
FYVE, RhoGEF and PH domain-containing protein 4 (766 aa, ~87 kDa) is encoded by the human FGD4 gene. This protein plays a role in regulation of the… (More)
National Institutes of Health

Papers overview

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2009
2009
PDZ-RhoGEF is a member of the regulator family of G protein signaling (RGS) domain-containing RhoGEFs (RGS-RhoGEFs) that link… (More)
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Review
2008
Review
2008
Frabin, together with, at least, FGD1, FGD2, FGD3 and FGD1-related Cdc42-GEF (FRG), is a member of a family of Cdc42-specific gua… (More)
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Highly Cited
2007
Highly Cited
2007
Charcot-Marie-Tooth (CMT) disorders are a clinically and genetically heterogeneous group of hereditary motor and sensory… (More)
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2004
2004
Cryptosporidium parvum invades target epithelia via a mechanism that involves host cell actin reorganization. We previously… (More)
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2004
2004
Mutations in faciogenital dysplasia protein (Fgd1) result in the human disease faciogenital dysplasia (FGDY). Fgd1 contains a… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Invadopodia are membrane protrusions into the extracellular matrix by aggressive tumour cells. These structures are… (More)
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2002
2002
BACKGROUND Frabin is an actin filament (F-actin)-binding protein with GDP/GTP exchange activity specific for Cdc42 small G… (More)
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1999
1999
We have recently isolated a novel actin filament-binding protein, named frabin. Frabin has one actin filament-binding domain (ABD… (More)
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1998
1998
We purified from rat brain a novel F-actin-binding protein with a Mr of about 105,000 (p105), which was estimated by SDS… (More)
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