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FYVE, RhoGEF and PH Domain-Containing Protein 4

Known as: FGD1-Related F-Actin-Binding Protein, Actin Filament-Binding Protein Frabin, Actin-Filament Binding Protein Frabin 
FYVE, RhoGEF and PH domain-containing protein 4 (766 aa, ~87 kDa) is encoded by the human FGD4 gene. This protein plays a role in regulation of the… 
National Institutes of Health

Related topics

Related topics

9 relations
Actin-Binding ProteinCytoskeletal ModelingDH DomainFGD4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The Role of Frabin (FGD4) in Aggressive Prostate Cancer
2014
2014
Abstract 5221: Association of miR-17-92 cluster and its target, Frabin, with development of aggressive prostate cancer
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Androgen blockade therapy has become the mainstay for… 
2009
2009
The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.
PDZ-RhoGEF is a member of the regulator family of G protein signaling (RGS) domain-containing RhoGEFs (RGS-RhoGEFs) that link… 
2008
2008
Mutations in FGD 4 encoding the Rho GDP / GTP Exchange Factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4 H
Charcot-Marie-Tooth (CMT) disorders are a clinically and genetically heterogeneous group of hereditary motor and sensory… 
2002
2002
Association of frabin with specific actin and membrane structures
Background: Frabin is an actin filament (F‐actin)‐binding protein with GDP/GTP exchange activity specific for Cdc42 small G… 
2001
2001
Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation
Frabin is a GDP/GTP exchange protein for Cdc42 with actin filament (F-actin)-binding activity. Cdc42 is a small GTP-binding… 
2001
2001
Identification of splicing variants of Frabin with partly different functions and tissue distribution.
Frabin is a GDP/GTP exchange protein for Cdc42 small G protein with actin filament-binding activity. Frabin consists of the actin… 
2000
2000
Importance of spatial activation of Cdc42 and Rac small G proteins by frabin for microspike formation in MDCK cells
Frabin is an actin filament (F‐actin)‐binding protein that shows GDP/GTP exchange activity for Cdc42 small G protein (Cdc42… 
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