FR 190997

The nonapeptide bradykinin (BK) is involved in the genesis of inflammation, edema and in pain mediation. As such, much effort has… (More)

The pharmacology of peptide and non-peptide bradykinin B2 receptor ligands was evaluated in the inositol phosphate (IP… (More)

Angiotensin Converting Enzyme Inhibitors (ACEI) like captopril and enalapril, can induce persistant cough in man. Noscapine, an… (More)

The present study examines the influence of kinins on the migratory capacity of human polymorphonuclear leukocytes under in vitro… (More)

Inhibitors of angiotensin I-converting enzyme (ACE) are very efficacious in the potentiation of the actions of bradykinin (BK… (More)

We tested whether FR190997, a nonpeptide B(2) agonist, prevented the development of hypertension in young spontaneously… (More)

Pharmacologic parameters for a novel non-peptide bradykinin (BK)-B2 receptor agonist, 8-[2,6-dichloro-3-[N-[(E)-4-(N… (More)

FR 190997, a new kinin B2 receptor agonist of non-peptide nature, has been studied in three isolated vessels: the human umbilical… (More)

1. The nonpeptide bradykinin (BK) B2 receptor antagonist, FR165649 (8-[2,6-dichloro-3-[N-[(E)-4-(N-methylcarbamoyl… (More)

Kinins, members of a family of peptides released from kininogens by the action of kallikreins, exhibit a variety of biological… (More)