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FPR1 gene

Known as: FPR1, FMLP RECEPTOR, FORMYL PEPTIDE RECEPTOR 1 
This gene plays a role in G protein-coupled receptor signal transduction and chemotaxis.
National Institutes of Health

Related topics

Related topics

9 relations
ChemotaxisFPR1 protein, humanG Protein-Coupled Receptor SignalingLigand Binding

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FPR1 wt Allele

Papers overview

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Highly Cited
1998
Highly Cited
1998
ADP-ribosylation Factor and Rho Proteins Mediate fMLP-dependent Activation of Phospholipase D in Human Neutrophils*
Activation of intact human neutrophils by fMLP stimulates phospholipase D (PLD) by an unknown signaling pathway. The small GTPase… 
Highly Cited
1997
Highly Cited
1997
Borrelia burgdorferi outer surface protein A (OspA) activates and primes human neutrophils.
Lyme disease is caused by infection with the spirochete Borrelia burgdorferi and is characterized by bacterial persistence and… 
Highly Cited
1992
Highly Cited
1992
Tyrosine phosphorylation and its possible role in superoxide production by human neutrophils stimulated with FMLP and IgG.
Highly Cited
1988
Highly Cited
1988
Occupancy of adenosine receptors raises cyclic AMP alone and in synergy with occupancy of chemoattractant receptors and inhibits membrane depolarization.
We have recently demonstrated that adenosine, acting via adenosine A2 receptors, inhibits generation of superoxide anions (O2… 
Highly Cited
1987
Highly Cited
1987
Receptor‐mediated ADP‐ribosylation of a phospholipase C‐stimulating G protein
Highly Cited
1987
Highly Cited
1987
Human neutrophil laminin receptors: activation-dependent receptor expression.
Activated human polymorphonuclear leukocytes (PMN) isolated from peripheral blood specifically bind 125I-laminin after… 
Highly Cited
1986
Highly Cited
1986
Cytochalasin B enhancement of the diacylglycerol response in formyl peptide-stimulated neutrophils.
Highly Cited
1984
Highly Cited
1984
Chemotactic peptide-induced changes in neutrophil actin conformation
The effect of the chemotatic peptide, N- formylmethionylleucylphenylalanine (FMLP), on actin conformation in human neutrophils… 
Highly Cited
1983
Highly Cited
1983
Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187.
The release of leukotriene B4 (LTB4) from human neutrophils and its relationship to degranulation induced by the divalent cation… 
Highly Cited
1979
Highly Cited
1979
Effects of a chemotactic factor, N-formylmethionyl peptide, on adherence, superoxide anion generation, phagocytosis, and microtubule assembly of human polymorphonuclear leukocytes.
FMLP promoted microtubule assembly in PMNs at concentrations which were chemotactic for the cells. At higher concentrations than… 
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