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FPR1 wt Allele

Known as: FMLP, FPR, Formyl Peptide Receptor 1 wt Allele 
Human FPR1 wild-type allele is located in the vicinity of 19q13.4 and is approximately 6 kb in length. This allele, which encodes fMet-Leu-Phe… 
National Institutes of Health

Related topics

Related topics

10 relations
19q13.4ChemotaxisFPR1 protein, humanFormyl Peptide Receptor 1 Signaling Pathway

Broader (1)

FPR1 gene

Papers overview

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Highly Cited
2008
Highly Cited
2008
Small Molecule Disruption of G Protein βγ Subunit Signaling Inhibits Neutrophil Chemotaxis and Inflammation
G protein βγ subunit-dependent signaling is important for chemoattractant-dependent leukocyte chemotaxis. Selective small… 
Highly Cited
2000
Highly Cited
2000
Kinase Pathways in Chemoattractant-Induced Degranulation of Neutrophils: The Role of p38 Mitogen-Activated Protein Kinase Activated by Src Family Kinases1
The aim of the present study was to investigate the role of tyrosine phosphorylation pathways in fMLP-induced exocytosis of the… 
Highly Cited
1998
Highly Cited
1998
p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation.
Mitogen-activated protein (MAP) kinase-mediated signal-transduction pathways convert extracellular stimulation into a variety of… 
Highly Cited
1997
Highly Cited
1997
A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature.
A two-step paradigm for leukocyte recruitment has been established in a number of tissues including the mesentery, skin, and… 
Highly Cited
1995
Highly Cited
1995
Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia
Highly Cited
1990
Highly Cited
1990
Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium.
The CD11/CD18 family of glycoproteins has been identified as a mediator of a number of adhesive interactions crucial to… 
Highly Cited
1989
Highly Cited
1989
Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine.
1. Lipoxin A4 (LXA4) and lipoxin B4 (LXB4) have been evaluated for their capacities to modulate neutrophil (PMN) migration and… 
Highly Cited
1989
Highly Cited
1989
Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis.
Activation of human neutrophils (PMN) is accompanied by rapid upregulation of CR1, the C3b receptor, and CR3, the iC3b receptor… 
Highly Cited
1987
Highly Cited
1987
Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion
The effect of flow on the adhesion of polymorphonuclear leukocytes (PMNL) to vascular endothelium was investigated using a… 
Highly Cited
1987
Highly Cited
1987
Effects of dietary supplementation with marine fish oil on leukocyte lipid mediator generation and function in rheumatoid arthritis.
Twelve patients with active rheumatoid arthritis supplemented their usual diet with 20 gm of Max-EPA fish oil, daily, for 6 weeks… 
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