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FOXO1 gene

Known as: Forkhead Box O1 Gene, FORKHEAD IN RHABDOMYOSARCOMA, FORKHEAD BOX O1A 
This gene is involved in transcriptional regulation and may play a role in myogenic growth and differentiation.
National Institutes of Health

Related topics

Related topics

7 relations
Alveolar rhabdomyosarcomaFOXO1A protein, humanHomo sapiensPAX3-FOXO1 Fusion Protein Expression

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FOXO1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MicroRNA-544 promotes colorectal cancer progression by targeting forkhead box O1
Dysregulation of microRNAs has been confirmed to serve an important role in cancer development and progression. However, the role… 
2017
2017
Hyperactive FOXO1 results in lack of tip stalk identity and deficient microvascular regeneration during kidney injury.
2014
2014
FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice
Highly Cited
2012
Highly Cited
2012
SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150.
Highly Cited
2011
Highly Cited
2011
Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.
Protein deacetylase Sirt1 has been implicated in the regulation of hepatic gluconeogenesis; however, the mechanisms are not fully… 
2011
2011
Glucagon-like peptide-1 and candesartan additively improve glucolipotoxicity in pancreatic β-cells.
Highly Cited
2009
Highly Cited
2009
FoxO1 Haploinsufficiency Protects Against High-Fat Diet–Induced Insulin Resistance With Enhanced Peroxisome Proliferator–Activated Receptor γ Activation in Adipose Tissue
OBJECTIVE Forkhead box O (FoxO) transcription factors represent evolutionarily conserved targets of insulin signaling, regulating… 
Highly Cited
2009
Highly Cited
2009
Inhibition of hypothalamic Foxo1 expression reduced food intake in diet‐induced obesity rats
Insulin signalling in the hypothalamus plays a role in maintaining body weight. The forkhead transcription factor Foxo1 is an… 
Highly Cited
2009
Highly Cited
2009
Acute exercise modulates the Foxo1/PGC‐1α pathway in the liver of diet‐induced obesity rats
PGC‐1α expression is a tissue‐specific regulatory feature that is extremely relevant to diabetes. Several studies have shown that… 
Highly Cited
2008
Highly Cited
2008
The regulation and function of the forkhead transcription factor, Forkhead box O1, is dependent on the progesterone receptor in endometrial carcinoma.
In many type I endometrial cancers, the PTEN gene is inactivated, which ultimately leads to constitutively active Akt and the… 
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