Skip to search formSkip to main contentSkip to account menu

FOXO1 wt Allele

Known as: FKHR, FKH1, FOXO1A Gene 
Human FOXO1 wild-type allele is located in the vicinity of 13q14.1 and is approximately 111 kb in length. This allele, which encodes forkhead box… 
National Institutes of Health

Related topics

Related topics

10 relations
13q14.1AKT Signaling PathwayAlveolar rhabdomyosarcomaAndrogen Receptor Regulation Pathway

Broader (1)

FOXO1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
FOXO1A is a target for HER2-overexpressing breast tumors.
Trastuzumab treatment has improved the overall survival of HER2-overexpressing breast cancer patients. However, many of these… 
2009
2009
Nickel and copper ion-induced stress signaling in human hepatoma cells: analysis of phosphoinositide 3′-kinase/Akt signaling
Nickel compounds may act as carcinogens, affecting both initiation and promotion stages of carcinogenesis due, in large parts, to… 
Highly Cited
2007
Highly Cited
2007
Chromosomal aberrations in prostate cancer.
Prostate cancer incidence is steadily increasing in Western industrialized countries where it has become the most common male… 
Highly Cited
2007
Highly Cited
2007
A novel role for p73 in the regulation of Akt-Foxo1a-Bim signaling and apoptosis induced by the plant lectin, Concanavalin A.
Virtually all human cancers encounter disruption of the "p53 network." From a therapeutic point of view, it is important to… 
2007
2007
Forkhead protein FKHR and its phosphorylated form p-FKHR in human prostate cancer.
Review
2005
Review
2005
Transcriptional regulation of neuronal genes and its effect on neural functions: expression and function of forkhead transcription factors in neurons.
Forkhead box transcription factor, class O (FOXO) is a mammalian homologue of DAF-16, which is known to regulate the lifespan of… 
Highly Cited
2004
Highly Cited
2004
FoxO1a can alter cell cycle progression by regulating the nuclear localization of p27kip in granulosa cells.
Forkhead transcription factors of the FOXO family are important downstream targets of the phosphatidylinositol 3-kinase pathway… 
Highly Cited
2003
Highly Cited
2003
Akt Modulates STAT3-mediated Gene Expression through a FKHR (FOXO1a)-dependent Mechanism*
The phosphatidylinositol 3-kinase/Akt pathway plays an important role in the signaling of insulin and other growth factors, which… 
2003
2003
Constitutive phosphorylation of FKHR transcription factor as a prognostic variable in acute myeloid leukemia.
2002
2002
Regulation of alkaline phosphatase promoter activity by forkhead transcription factor FKHR.
Alkaline phosphatase (ALP) is a basic marker of osteoblast maturation and osteogenesis. However, the mechanisms of the ALP gene… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)