FOLH1 gene

Known as: FOLH, GLUTAMATE CARBOXYPEPTIDASE II, folate hydrolase (prostate-specific membrane antigen) 1 
This gene plays a role in folate metabolism. It is also involved in neuronal transmission.
National Institutes of Health

Papers overview

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2014
2014
BACKGROUND AND AIMS The characterization of candidate gene polymorphisms in elderly populations is an important tool for the… (More)
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2009
2009
Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a zinc-dependent exopeptidase and an important therapeutic target for… (More)
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2008
2008
Human glutamate carboxypeptidase II (GCPII) is involved in neuronal signal transduction and intestinal folate absorption by means… (More)
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2008
2008
BACKGROUND Folate is an essential nutrient that supports nucleotide synthesis and biological methylation reactions. Diminished… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Because glutamate carboxypeptidase II (GCPII) regulates both folate absorption and activation of N-methyl-d-aspartic… (More)
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2004
2004
The peptide neurotransmitter N-acetylaspartylglutamate is inactivated by extracellular peptidase activity following synaptic… (More)
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2003
2003
Neural tube defects (NTDs) have a well-established genetic basis, although no single genetic factor has been identified as a… (More)
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2002
2002
Glutamate carboxypeptidase II (GCPII) hydrolyzes polyglutamyl folates before their absorption. Recently, a 1561 C>T polymorphism… (More)
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2001
2001
Prostate-specific membrane antigen (PSMA) is an integral membrane protein that is highly expressed on the surface of prostate… (More)
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1998
1998
Prostate-specific membrane antigen (PSMA) is a 100 kDa type II transmembrane protein with folate hydrolase and NAALAdase activity… (More)
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