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FOLH1 gene

Known as: FOLH, GLUTAMATE CARBOXYPEPTIDASE II, folate hydrolase (prostate-specific membrane antigen) 1 
This gene plays a role in folate metabolism. It is also involved in neuronal transmission.
National Institutes of Health

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FOLH1 wt Allele
HydrolysisMolecular TransportNAALADL1 geneSynaptic Transmission

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Glutamate carboxypeptidase II (GCPII) is a membrane protease overexpressed by prostate cancer cells and detected in the… 
2017
2017
PSMA-targeted bispecific Fab conjugates that engage T cells.
2014
2014
Association of seven functional polymorphisms of one-carbon metabolic pathway with total plasma homocysteine levels and susceptibility to Parkinson's disease among South Indians
2014
2014
Pharmacokinetics and PET imaging properties of two recombinant anti‐PSMA antibody fragments in comparison to their parental antibody
Radioimmunoimaging with disease‐specific tracers can be advantageous compared to that with nonspecific tracers for the imaging of… 
2008
2008
Dysregulation of glutamate carboxypeptidase II in psychiatric disease
2006
2006
Immune responses against PSMA after gene-based vaccination for immunotherapy – A: results from immunizations in animals
Two plasmid DNA vaccines, encoding either products that are retained in the cytosol and degraded in the proteasome (tVacs; hPSMAt… 
2003
2003
Identification of naturally processed helper T-cell epitopes from prostate-specific membrane antigen using peptide-based in vitro stimulation.
PURPOSE There is growing evidence that CD4(+) helper T lymphocytes (HTLs) play an essential role in the induction and long-term… 
2003
2003
NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen.
2003
2003
Expression pattern of mouse homolog of prostate‐specific membrane antigen (FOLH1) in the transgenic adenocarcinoma of the mouse prostate model
Prostate specific membrane antigen (PSMA) is expressed on the plasma membrane of normal prostate and in primary and metastatic… 
2002
2002
The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort.
Glutamate carboxypeptidase II (GCPII) hydrolyzes polyglutamyl folates before their absorption. Recently, a 1561 C>T polymorphism… 
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