FLT4 gene

Known as: VEGFR3, fms related tyrosine kinase 4, FLT4 
This gene plays an essential role in the development of embryonic cardiovasculature and lymphatic vessel formation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
010203019792017

Papers overview

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2015
2015
Angiogenesis, the formation of new blood vessels, is regulated by vascular endothelial growth factors (VEGFs) and their receptors… (More)
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2013
2013
RATIONALE Mutations in vascular endothelial growth factor (VEGF) receptor-3 (VEGFR3 or FLT4) cause Milroy disease, an autosomal… (More)
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Highly Cited
2011
Highly Cited
2011
Angiosarcoma (AS) is a distinct group of sarcomas characterized by upregulation of vascular-specific receptor tyrosine kinases… (More)
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2003
2003
Polycomb group (PcG) proteins are required to maintain stable repression of the homeotic genes and others throughout development… (More)
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Highly Cited
2000
Highly Cited
2000
Hereditary lymphedema is a chronic swelling of limbs due to dysfunction of lymphatic vessels. An autosomal dominant, congenital… (More)
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2000
2000
PURPOSE Our objective was to verify the fiber anatomy of the posterior cruciate ligament (PCL) and to measure the main dimensions… (More)
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1997
1997
FLT4 represents a recently cloned member of class III receptor tyrosine kinases which include receptors for the angiogenic growth… (More)
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1995
1995
In humans, the FLT4 gene encodes two isoforms of a tyrosine kinase receptor, which differ in their carboxy terminal regions. As… (More)
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1993
1993
Three receptor tyrosine kinases, FLT1, FLK1 and FLT4, contain seven immunoglobin-like domains in their extracellular region and… (More)
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Highly Cited
1992
Highly Cited
1992
The fms-like tyrosine kinase 4 (FLT4) complementary DNA was cloned from a human HEL erythroleukemia cell library by polymerase… (More)
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